GPCR G2A Antibody, ALEXA FLUOR 350
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Catalog numberbs-13508R-A350
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PricePlease ask
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Size100ul
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Long nameGPCR G2A Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
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Also known asAnti-GPCR G2A PAb ALEXA FLUOR 350
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 350
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenGPCR G2A
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SpecificityThis is a highly specific antibody against GPCR G2A.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human G Protein Coupled Receptor G2A
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Gene ID Number29933
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenG2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1). G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, and it is more highly detected in pro-B cells, while lower expression is observed in immature B cells and pre-B cells (1,2). G2A is expressed throughout T cell maturation, and it is further increased in response to T-cell activation (3). Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1,4). G2A is also able to attenuate the proliferative effects of Bcr-Abl, a chimeric tyrosine kinase oncogene, suggesting that G2A possesses anti-oncogenic properties (5). The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, where it is required for ubiquitination and proteolytic degradation (6).
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission343nm/442nm
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SynonymsG Protein Coupled Receptor G2A; G Protein Coupled Receptor G2A; G2 accumulation protein; G2A; GP132_HUMAN; GPR132; Probable G-protein coupled receptor 132.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 350
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French translationanticorps
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Gene target
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Gene symbolGPR132, OXER1, HCAR1, GPBAR1, GPER1
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Short nameAnti-GPCR G2A
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 350
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Alternative nameGPCR G2A Polyclonal Antibody, ALEXA FLUOR 350
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameG protein-coupled receptor 132
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-12-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G protein-coupled receptors, Class A orphans
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameoxoeicosanoid receptor 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-04-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Leukotriene receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namehydroxycarboxylic acid receptor 1
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Synonyms gene
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Synonyms gene name
- G protein-coupled receptor 104
- G protein-coupled receptor 81
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-01-20
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Entrez gene record
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Pubmed identfication
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Classification
- Hydroxycarboxylic acid receptors
Gene info
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Identity
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Gene
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Long gene nameG protein-coupled bile acid receptor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-01-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G protein-coupled bile acid receptor
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameG protein-coupled estrogen receptor 1
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Synonyms gene
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Synonyms gene name
- G protein-coupled receptor 30
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G protein-coupled estrogen receptor
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data