GPCR G2A Antibody, ALEXA FLUOR 594

• Catalog number
  bs-13508R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  GPCR G2A Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-GPCR G2A PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GPCR G2A
• Specificity
  This is a highly specific antibody against GPCR G2A.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human G Protein Coupled Receptor G2A
• Gene ID Number
  29933
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1). G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, and it is more highly detected in pro-B cells, while lower expression is observed in immature B cells and pre-B cells (1,2). G2A is expressed throughout T cell maturation, and it is further increased in response to T-cell activation (3). Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1,4). G2A is also able to attenuate the proliferative effects of Bcr-Abl, a chimeric tyrosine kinase oncogene, suggesting that G2A possesses anti-oncogenic properties (5). The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, where it is required for ubiquitination and proteolytic degradation (6).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  G Protein Coupled Receptor G2A; G Protein Coupled Receptor G2A; G2 accumulation protein; G2A; GP132_HUMAN; GPR132; Probable G-protein coupled receptor 132.
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  GPCR   G2A  
• Gene symbol
  GPR132, OXER1, HCAR1, GPBAR1, GPER1
• Short name
  Anti-GPCR G2A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  GPCR G2A Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17482
• Gene
  GPR132
• Long gene name
  G protein-coupled receptor 132
• Synonyms
  • G2A
• Synonyms name
  • G2 accumulation
• GenBank acession
  • AF083955
• Locus
  14q32.33
• Discovery year
  2003-12-10
• Entrez gene record
  29933
• Pubmed identfication
  • 12086852
• RefSeq identity
  • NM_013345
• Classification
  • G protein-coupled receptors, Class A orphans
• VEGA ID
  OTTHUMG00000140173

Gene info

• Identity
  HGNC:24884
• Gene
  OXER1
• Long gene name
  oxoeicosanoid receptor 1
• Synonyms
  • GPCR
  • TG1019
  • GPR170
• Synonyms name
  • 5-oxo-ETE acid G-protein-coupled receptor 1
  • OXE receptor
• GenBank acession
  • AB083055
• Locus
  2p21
• Discovery year
  2004-04-02
• Entrez gene record
  165140
• Pubmed identfication
  • 12065583
  • 15001665
• RefSeq identity
  • NM_148962
• Classification
  • Leukotriene receptors
• VEGA ID
  OTTHUMG00000128643

Gene info

• Identity
  HGNC:4532
• Gene
  HCAR1
• Long gene name
  hydroxycarboxylic acid receptor 1
• Synonyms gene
  • GPR104
  • GPR81
• Synonyms gene name
  • G protein-coupled receptor 104
  • G protein-coupled receptor 81
• Synonyms
  • HCA1
  • FKSG80
  • TA-GPCR
  • LACR1
• Synonyms name
  • lactate receptor 1
• GenBank acession
  • AF411110
• Locus
  12q24.31
• Discovery year
  2000-01-20
• Entrez gene record
  27198
• Pubmed identfication
  • 11574155
  • 19047060
  • 18952058
  • 21454438
• Classification
  • Hydroxycarboxylic acid receptors

Gene info

• Identity
  HGNC:19680
• Gene
  GPBAR1
• Long gene name
  G protein-coupled bile acid receptor 1
• Synonyms
  • BG37
  • GPCR
  • TGR5
  • M-BAR
  • GPCR19
  • GPR131
  • MGC40597
• GenBank acession
  • AB086170
• Locus
  2q35
• Discovery year
  2003-01-24
• Entrez gene record
  151306
• Pubmed identfication
  • 12419312
• RefSeq identity
  • NM_001077191
• Classification
  • G protein-coupled bile acid receptor
• VEGA ID
  OTTHUMG00000155203

Gene info

• Identity
  HGNC:4485
• Gene
  GPER1
• Long gene name
  G protein-coupled estrogen receptor 1
• Synonyms gene
  • CMKRL2
  • GPR30
  • GPER
• Synonyms gene name
  • G protein-coupled receptor 30
• Synonyms
  • FEG-1
  • GPCR-Br
  • LERGU
  • LERGU2
  • DRY12
  • LyGPR
  • CEPR
• GenBank acession
  • U63917
• Locus
  7p22.3
• Discovery year
  1997-06-12
• Entrez gene record
  2852
• Pubmed identfication
  • 9479505
  • 17655271
• RefSeq identity
  • NM_001039966
• Classification
  • G protein-coupled estrogen receptor
• VEGA ID
  OTTHUMG00000023680

MeSH Data

• Name
  Polymerase Chain Reaction
• Concept
  Scope note: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
• Tree numbers
  • E05.393.620.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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