Recombinant Human Peroxiredoxin-4/PRDX4 Protein(N-6His)

• Catalog number
  PKSH032884-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  Peroxiredoxin-4; Antioxidant Enzyme AOE372; AOE37-2; Peroxiredoxin IV; Prx-IV; Thioredoxin Peroxidase AO372; Thioredoxin-Dependent Peroxide Reductase A0372; PRDX4
• Activity
  NA
• Sequence
  Trp38-Asn271
• Fusion tag
  N-6His
• Accession
  Q13162
• Expressed Host
  E.coli
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  33.8 kDa
• AP Mol Mass
  30 kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.2.
• Background
  Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
• Technical data
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Peroxiredoxin-4/PRDX4   Protein   N-6His  
• Gene symbol
  PRDX4
• Short name
  Recombinant Peroxiredoxin-4/PRDX4 Protein(N-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Peroxiredoxin-4/PRDX4 Protein(N-6His)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:17169
• Gene
  PRDX4
• Long gene name
  peroxiredoxin 4
• Synonyms
  • AOE37-2
• GenBank acession
  • U25182
• Locus
  Xp22.11
• Discovery year
  2001-11-14
• Entrez gene record
  10549
• Pubmed identfication
  • 9388242
• RefSeq identity
  • NM_006406
• Classification
  • Peroxiredoxins
• VEGA ID
  OTTHUMG00000021253
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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