CD11b Antibody

• Catalog number
  GEN438450
• Price
  Please ask
• Size
  100ug

• Also known as
  CD11b
• Other names
  integrin alpha-M isoform 2; Integrin alpha-M; integrin alpha-M; CR-3 alpha chain; antigen CD11b (p170); leukocyte adhesion receptor MO1; CD11 antigen-like family member B; macrophage antigen alpha polypeptide; cell surface glycoprotein MAC-1 subunit alpha; neutrophil adherence receptor alpha-M subunit; integrin, alpha M (complement component 3 receptor 3 subunit); CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD_antigen: CD11b
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  ITGAM
• Gene name synonims
  N/A
• Other gene names
  ITGAM; ITGAM; CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; CD11B; CR3A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2b, kappa
• Clone
  C11b/660
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin åM combines with the Integrin ?2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin åM/?2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC), Immunofluorescence (IF), Functional Studies, Immunoprecipitation (IP), Immunohistology (IH)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD11b  
• Gene symbol
  ITGAM, CD11B
• Short name
  CD11b Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-CD11b
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6149
• Gene
  ITGAM
• Long gene name
  integrin subunit alpha M
• Synonyms gene
  • CR3A
  • CD11B
• Synonyms gene name
  • integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide)
  • integrin, alpha M (complement component 3 receptor 3 subunit)
• Synonyms
  • MAC-1
  • CD11b
• Synonyms name
  • complement component 3 receptor 3 subunit
  • macrophage-1 antigen alpha subunit
• GenBank acession
  • J03925
• Locus
  16p11.2
• Discovery year
  1988-08-05
• Entrez gene record
  3684
• RefSeq identity
  • NM_000632
• Classification
  • Integrin alpha subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000176612
• Locus Specific Databases
  • LRG_1333

Gene info

• Identity
  HGNC:1626
• Gene
  CD11B
• Long gene name
  ERBB receptor feedback inhibitor 1
• Synonyms
  • MIG-6
  • GENE-33
  • RALT
  • [HGNC:6149](/data/gene-symbol-report/#!/hgnc_id/HGNC:6149)
  • ERRFI1
• GenBank acession
  • BC025337
• Locus
  1p36.23
• Discovery year
  2005-08-23
• Entrez gene record
  54206
• Pubmed identfication
  • 10749885
  • 2780291
  • 12226756
  • 11003669
• RefSeq identity
  • NM_018948
• VEGA ID
  OTTHUMG00000001221

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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