MOUSE ANTI RAT CD11b

• Catalog number
  MBS213105
• Price
  Please ask
• Size
  5x0.25 mg

• Products_type
  Antibody
• Products_short_name
  [CD11b]
• Other_names
  [CD11b, partial; CD11b; integrin alpha-M; CD11b]
• Products_gene_name
  [CD11b]
• Other_gene_names
  [ITGAM; CD11b; CD11B]
• Clonality
  Monoclonal
• Clone
  [ED7]
• Specificity
  This item recognises a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. Like ED8, ED7 recognises small ramified microglia in the central nervous system. No other cell types are positive for ED7, except for the cilia of the bronchus epithelium. The recognised antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules (CD11b/CD18). ED7 and ED8 may recognise closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 0.5 mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  Immunohistology Frozen*, Flow cytometry (FC/FACS), Functional Assays (FN)*
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus, Rattus norvegicus
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

• Gene target
  CD11b  
• Gene symbol
  ITGAM, CD11B
• Short name
  MOUSE ANTI CD11b
• Technique
  Mouse, anti, antibody to, mouses
• Host
  Mouse
• Isotype
  IgG1
• Species
  Rat, Mouses, Rats
• Alternative name
  MOUSE antibody to RAT CD11b
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:6149
• Gene
  ITGAM
• Long gene name
  integrin subunit alpha M
• Synonyms gene
  • CR3A
  • CD11B
• Synonyms gene name
  • integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide)
  • integrin, alpha M (complement component 3 receptor 3 subunit)
• Synonyms
  • MAC-1
  • CD11b
• Synonyms name
  • complement component 3 receptor 3 subunit
  • macrophage-1 antigen alpha subunit
• GenBank acession
  • J03925
• Locus
  16p11.2
• Discovery year
  1988-08-05
• Entrez gene record
  3684
• RefSeq identity
  • NM_000632
• Classification
  • Integrin alpha subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000176612
• Locus Specific Databases
  • LRG_1333

Gene info

• Identity
  HGNC:1626
• Gene
  CD11B
• Long gene name
  ERBB receptor feedback inhibitor 1
• Synonyms
  • MIG-6
  • GENE-33
  • RALT
  • [HGNC:6149](/data/gene-symbol-report/#!/hgnc_id/HGNC:6149)
  • ERRFI1
• GenBank acession
  • BC025337
• Locus
  1p36.23
• Discovery year
  2005-08-23
• Entrez gene record
  54206
• Pubmed identfication
  • 10749885
  • 2780291
  • 12226756
  • 11003669
• RefSeq identity
  • NM_018948
• VEGA ID
  OTTHUMG00000001221

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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