Fibronectin

• Catalog number
  GEN438210
• Price
  Please ask
• Size
  100ug

• Also known as
  Fibronectin
• Other names
  fibronectin isoform 3 preproprotein; Fibronectin; fibronectin; cold-insoluble globulin; migration-stimulating factor; fibronectin 1; Cold-insoluble globulin; CIG
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  FN1
• Gene name synonims
  N/A
• Other gene names
  FN1; FN1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; FN; FN; CIG
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa
• Clone
  TV-1
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens), Pig, Mouse (Mus musculus), Rat (Rattus norvegicus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)

• Gene target
  Fibronectin  
• Gene symbol
  FANK1, FNDC3A, FLRT3
• Short name
  Fibronectin
• Alternative name
  Anti-Fibronectin

Gene info

• Identity
  HGNC:23527
• Gene
  FANK1
• Long gene name
  fibronectin type III and ankyrin repeat domains 1
• Synonyms gene name
  • fibronectin type 3 and ankyrin repeat domains 1
• GenBank acession
  • BC024189
• Locus
  10q26.2
• Discovery year
  2003-11-21
• Entrez gene record
  92565
• Pubmed identfication
  • 17604233
• RefSeq identity
  • NM_145235
• Classification
  • Ankyrin repeat domain containing
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000019241

Gene info

• Identity
  HGNC:20296
• Gene
  FNDC3A
• Long gene name
  fibronectin type III domain containing 3A
• Synonyms gene
  • FNDC3
• Synonyms gene name
  • fibronectin type III domain containing 3
• Synonyms
  • bA203I16.5
  • KIAA0970
• GenBank acession
  • AB023187
• Locus
  13q14.2
• Discovery year
  2004-04-16
• Entrez gene record
  22862
• RefSeq identity
  • NM_014923
• Classification
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000016911

Gene info

• Identity
  HGNC:3762
• Gene
  FLRT3
• Long gene name
  fibronectin leucine rich transmembrane protein 3
• GenBank acession
  • AF169677
• Locus
  20p12.1
• Discovery year
  1999-10-29
• Entrez gene record
  23767
• Pubmed identfication
  • 10644439
• RefSeq identity
  • NM_013281
• Classification
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000031914

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