Fibronectin

• Catalog number
  MBS438210
• Price
  Please ask
• Size
  0.1 mg (Without BSA & Azide at 1mg/mL)

• Products_type
  Antibody
• Products_short_name
  [Fibronectin]
• Products_name_syn
  [Cold insoluble globulin (CIG); FINC; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor (MSF); Ugl-Y3]
• Other_names
  [fibronectin isoform 3 preproprotein; Fibronectin; fibronectin; cold-insoluble globulin; migration-stimulating factor; fibronectin 1; Cold-insoluble globulin; CIG]
• Products_gene_name
  [FN1]
• Other_gene_names
  [FN1; FN1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; FN; FN; CIG]
• Clonality
  Monoclonal
• Clone
  [TV-1]
• Reactivity
  Human, Pig, Mouse and Rat. Others-not known.
• Specificity
  Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)

• Gene target
  Fibronectin  
• Gene symbol
  FANK1, FNDC3A, FLRT3
• Short name
  Fibronectin
• Host
  Mouse
• Isotype
  IgG1, kappa
• Alternative name
  Fibronectin

Gene info

• Identity
  HGNC:23527
• Gene
  FANK1
• Long gene name
  fibronectin type III and ankyrin repeat domains 1
• Synonyms gene name
  • fibronectin type 3 and ankyrin repeat domains 1
• GenBank acession
  • BC024189
• Locus
  10q26.2
• Discovery year
  2003-11-21
• Entrez gene record
  92565
• Pubmed identfication
  • 17604233
• RefSeq identity
  • NM_145235
• Classification
  • Ankyrin repeat domain containing
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000019241

Gene info

• Identity
  HGNC:20296
• Gene
  FNDC3A
• Long gene name
  fibronectin type III domain containing 3A
• Synonyms gene
  • FNDC3
• Synonyms gene name
  • fibronectin type III domain containing 3
• Synonyms
  • bA203I16.5
  • KIAA0970
• GenBank acession
  • AB023187
• Locus
  13q14.2
• Discovery year
  2004-04-16
• Entrez gene record
  22862
• RefSeq identity
  • NM_014923
• Classification
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000016911

Gene info

• Identity
  HGNC:3762
• Gene
  FLRT3
• Long gene name
  fibronectin leucine rich transmembrane protein 3
• GenBank acession
  • AF169677
• Locus
  20p12.1
• Discovery year
  1999-10-29
• Entrez gene record
  23767
• Pubmed identfication
  • 10644439
• RefSeq identity
  • NM_013281
• Classification
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000031914

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