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CEA 5F2 Monoclonal Antibody ALEXA FLUOR

CEA 5F2 Monoclonal Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bsm-4793M-A350 | CEA (5F2) Monoclonal Antibody, ALEXA FLUOR 350 size: 100ul | 377.54 USD

Long name CEA (5F2) Monoclonal Antibody, ALEXA FLUOR 350 Conjugated
Also known as Anti-CEA MAb ALEXA FLUOR 350
Conjugated with ALEXA FLUOR® 350
Excitation emission 343nm/442nm
Properties For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation Alexa Fluor,ALEXA FLUOR 350
About Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
French translation anticorps
Label ALEXA FLUOR 350
Alternative name CEA (5F2) monoclonal (Antibody to), ALEXA FLUOR 350
1. Gene info
Identity1819
Long gene name carcinoembryonic antigen related cell adhesion molecule 7
Synonyms gene
Synonyms gene name
  • carcinoembryonic antigen-related cell adhesion molecule 7
Synonyms
GenBank acession
Locus19q13.2
Discovery year 1991-09-12
Entrez gene record1087
Pubmed identfication
RefSeq identity
Classification
  • Immunoglobulin like domain containing
  • V-set domain containing
  • Carcinoembryonic antigen related cell adhesion molecule family
Havana BLAST/BLATOTTHUMG00000151063
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedIn a cohort with non-small cell lung cancer, the mutation rates in EGFR exons 19 and 21 were 23.2% and 14.9%, respectively, with both in 3.81%. Mutation was more common in non-smokers than smokers, and in adenocarcinoma more than squamous cell carcinoma.
results from transgenic mouse models up-regulated indicate non-mutated adhesion molecules could have a significant instrumental role in human cancer
Study shows that it is possible to use ultrasound to amplify and localize the source of CEA levels in blood of tumor-bearing mice and will allow for a previously undescribed way to determine the presence and localization of disease more accurately.
Elevated levels of CEA are associated with pancreatic cancer and new-onset diabetes.
Data show that Ad5 immune mice bearing CEA-expressing tumors that were treated with Ad5 [E1-, E2b-]-CEA had increased anti-tumor response as compared with Ad5 [E1-]-CEA treated mice.
Vaccination with the plasmid for the triple repeated CEA peptides induced stronger Th1 responses
preoperative expression level is a prognostic factor in patients with stage I non-small cell lung cancer
The significant expression of IMP3 and CEA in less well-differentiated foci of mucinous MDA may be helpful in the diagnosis of mucinous MDA to some extent.
Data indicate that serum carcino-embryonic antigen (CEA) has a tendency to increase over time in patients with urinary diversion (UD) but is not a valuable marker of secondary neoplasms in these patients.
upregulated transcription correlates with tumor size in Non-Small-Cell Lung Cancer
Product images
    #bs#.jpgHT29 Cell lysates probed with CEA (5F2) Monoclonal Antibody, unconjugated (bsm-4793M) at 1:300 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.#.png
Product files

bsm-4793M-A488 | CEA (5F2) Monoclonal Antibody, ALEXA FLUOR 488 size: 100ul | 377.54 USD

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bsm-4793M-A555 | CEA (5F2) Monoclonal Antibody, ALEXA FLUOR 555 size: 100ul | 377.54 USD

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bsm-4793M-A594 | CEA (5F2) Monoclonal Antibody, ALEXA FLUOR 594 size: 100ul | 377.54 USD

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bsm-4793M-A647 | CEA (5F2) Monoclonal Antibody, ALEXA FLUOR 647 size: 100ul | 377.54 USD

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Modification Unmodified
Clonality Monoclonal
Category Conjugated Primary Antibodies
Host Organism Mouse (Mus musculus)
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CEA/CEACAM5
Specificity This is a highly specific antibody against CEA.
Tested applications IF(IHC-P)
Clone 5F2
Modification Site None
Synonyms Carcino Embryonic Antigen CEA; CEACAM 5; CEACAM-5; Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; CD66e; CD66e antigen; CEA; CEACAM5; DKFZp781M2392; Meconium antigen 100.
Purification Purified by Protein G.
Crossreactivity Human
Gene ID Number 1048
Recommended dilutions IF(IHC-P)(1:50-200)
Background of the antigen CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
Concentration 1ug per 1ul
Target Antigen CEA
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Gene targetCEA 5F2 Monoclonal
Short name CEA (5F2) Monoclonal Antibody,
Technique Antibody
Alternative technique antibodies
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