Anti-CEA (3G7) Monoclonal, ALEXA Fluor 594
-
Catalog numberGENTObsm-4792M-A594
-
PricePlease ask
-
Size100 microliters
-
-
TypeConjugated Primary Antibody
-
Conjugated withALEXA FLUOR 594
-
Host organismMouse (Mus musculus)
-
Target Protein PeptideCEA
-
SpecificityHighly specific antibody against CEA
-
ModificationNot modified
-
ClonalityMonoclonal Antibodies
-
Clone3G7
-
Concentration1ug per 1ul
-
Antigen SourceKLH conjugated synthetic peptide derived from Human CEA/CEACAM5
-
Gene ID1048
-
ApplicationsIF(IHC-P)
-
Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
-
Cross Reactive speciesHuman (Homo sapiens)
-
Cross Reactive Species detailsNo significant cross reactivity is observed
-
Background informationCEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
-
Purification methodPurified by Protein G.
-
StorageAqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
-
Excitation emission590nm/617nm
-
SynonymsCarcino Embryonic Antigen CEA; CEACAM 5; CEACAM-5; Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; CD66e; CD66e antigen; CEA; CEACAM5; DKFZp781M2392; Meconium antigen 100.
-
Alternative name 1CEA (3G7) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated
-
Alternative name 2CEA (3G7) Monoclonal anti-, ALEXA FLUOR 594 Conjugated
-
AdvisoryCycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
-
PropertiesFor facs or microscopy Alexa 1 conjugate.
-
ConjugationAlexa Fluor, ALEXA FLUOR® 594
-
ConjugatedAlexa conjugate 1
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
Gene target
-
Gene symbolCEACAM7, CEACAM5, PSG2
-
Short nameAnti-CEA (3G7) Monoclonal,
-
Techniqueanti-, anti, antibody to, antibodies, Monoclonals or monoclonal antibodies
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 594
-
Alternative nameAntibody toCEA (3G7) monoclonal, ALEXA Fluor 594
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameCEA cell adhesion molecule 7
-
Synonyms gene
-
Synonyms gene name
- carcinoembryonic antigen-related cell adhesion molecule 7
- carcinoembryonic antigen related cell adhesion molecule 7
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1991-09-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- V-set domain containing
- CEA cell adhesion molecule family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameCEA cell adhesion molecule 5
-
Synonyms gene
-
Synonyms gene name
- carcinoembryonic antigen-related cell adhesion molecule 5
- carcinoembryonic antigen related cell adhesion molecule 5
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
RefSeq identity
-
Classification
- I-set domain containing
- V-set domain containing
- CEA cell adhesion molecule family
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namepregnancy specific beta-1-glycoprotein 2
-
Synonyms gene
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1991-06-06
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Pregnancy specific glycoproteins
- V-set domain containing
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data