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Products_type
Recombinant Protein
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Products_short_name
[Receptor tyrosine-protein kinase erbB-3 (ERBB3)]
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Other_names
[receptor tyrosine-protein kinase erbB-3 isoform s; Receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; erb-b2 receptor tyrosine kinase 3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3]
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Products_gene_name
[ERBB3]
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Other_gene_names
[ERBB3; ERBB3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; HER3]
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Purity
>85% (SDS-PAGE)
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Form
Lyophilized or liquid (Format to be determined during the manufacturing process)
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Storage_stability
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
ERBB3
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Short name
Recombinant Receptor tyrosine-protein kinase erbB-3 (ERBB3), partial
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
E Coli or Yeast or Baculovirus or Mammalian Cell
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Species
Human, Humans
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Alternative name
Rec. H. sapiens Receptor tyrosine-protein phosphorylation catalyst erbB-3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)), partial
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Alternative technique
rec
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Alternative to gene target
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), c-erbB-3 and c-erbB3 and ErbB-3 and erbB3-S and HER3 and LCCS2 and MDA-BF-1 and p180-ErbB3 and p45-sErbB3 and p85-sErbB3, ERBB3 and IDBG-39824 and ENSG00000065361 and 2065, transferase activity, Extracellular, Erbb3 and IDBG-197943 and ENSMUSG00000018166 and 13867, ERBB3 and IDBG-636302 and ENSBTAG00000010444 and 785655
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