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Products_type
Antibody
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Products_short_name
[ErbB3]
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Products_name_syn
[Anti -ErbB3, CT (Receptor Tyrosine-protein Kinase erbB-3, Proto-oncogene-like Protein c-ErbB-3, Tyrosine Kinase-type Cell Surface Receptor HER3, HER3)]
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Other_names
[ERBB3 protein; Receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3]
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Other_gene_names
[ERBB3; ERBB3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; HER3]
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Clonality
Polyclonal
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Reactivity
Human
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Specificity
Recognizes human ERBB3. Species sequence homology: Canine, mouse and rat.
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Purity
Affinity Purified Purified by immunoaffinity chromatography.
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Form
Supplied as a liquid in TBS, 0.5% BSA, 0.02% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
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Description
For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
ERBB3
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Short name
ErbB3, CT (Receptor Tyrosine-protein Kinase erbB-3, Proto-oncogene-like Protein c-ErbB-3, Tyrosine Kinase- Surface Receptor HER3, HER3)
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Host
Goat
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Alternative name
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), CT (Receptor Tyrosine-protein phosphorylation catalyst erbB-3, Proto-oncogene-like Protein c-ErbB-3, Tyrosine phosphorylation catalyst-classification cellular Surface Receptor HER3, HER3)
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Alternative to gene target
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), c-erbB-3 and c-erbB3 and ErbB-3 and erbB3-S and HER3 and LCCS2 and MDA-BF-1 and p180-ErbB3 and p45-sErbB3 and p85-sErbB3, ERBB3 and IDBG-39824 and ENSG00000065361 and 2065, transferase activity, Extracellular, Erbb3 and IDBG-197943 and ENSMUSG00000018166 and 13867, ERBB3 and IDBG-636302 and ENSBTAG00000010444 and 785655
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Tissue
cell
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