PathwayReady™ PI3-K/Akt/mTOR Signaling Inhibitor Panel
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Catalog numberK857-11
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PricePlease ask
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Size11 inhibitors
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Alternative_namePI3-K/Akt/mTOR Signaling Inhibitor Panel, PathwayReady™
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DescriptionA convenient set consisting of eleven inhibitors useful for the study of PI3-K/Akt/mTOR pathway. The 11 inhibitors are: 1 mg of Akt Inhibitor, Isozyme-selective (Cat. No. 1708-1), 5 mg of BEZ-235 (Cat. No. 1626-5), 5 mg of LY-294002 (Cat. No. 1667-5), 1 mg of mTOR Inhibitor Ku-0063794 (Cat. No. 1779-1), 1 mg of PI-103 (Cat. No. 1728-1), 1 mg of PI3-Kγ Inhibitor, AS-605240 (Cat. No. 1780-1), 1 mg of PP242 (Cat. No. 1658-1), 1 mg of Rapamycin (Cat. No. 1568-1), 1 mg of TGX-221 (Cat. No. 1781-1), 1 mg of Triciribine (Cat. No. 1707-1), and 1 mg of Wortmannin (Cat. No. 1670-1).
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CAS NumberSee under the individual product
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Structure AvailableSee under the individual product
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Salt FormNo
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Molecular FormulaSee under the individual product
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Molecular WeightSee under the individual product
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Cell PermeableYes
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Purity≥95% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA PI3-K/Akt/mTOR Signaling Inhibitor Panel
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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SMILESN/A
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InChiN/A
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InChi KeyN/A
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MSDS AvailableYes
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Additional descriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
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Gene target
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Gene symbolPIK3C2B, PIK3CA, PIK3C2A, H4C13, PIK3R5, TUBA1B, RAP2A, GPC4
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Short namePathwayReady™ PI3-K/Akt/mTOR Signaling Inhibitor Panel
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Alternative namePathwayReady™ PI3-K/Akt/Mammalian target on rapamycin Signaling suppressor Panel
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Alternative to gene targetmechanistic target of rapamycin (serine/threonine kinase), FRAP and FRAP1 and FRAP2 and RAFT1 and RAPT1, MTOR and IDBG-89258 and ENSG00000198793 and 2475, transferase activity, nuclei, Mtor and IDBG-204403 and ENSMUSG00000028991 and 56717, MTOR and IDBG-632731 and ENSBTAG00000015325 and 100139219
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Tissuepanel
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Gene info
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Identity
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Gene
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Long gene namephosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
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Synonyms gene name
- phosphoinositide-3-kinase, class 2, beta polypeptide
- phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-05-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Phosphatidylinositol 3-kinase subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
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Synonyms gene name
- phosphoinositide-3-kinase, catalytic, alpha polypeptide
- phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
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Synonyms
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Locus
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Discovery year1994-07-15
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Entrez gene record
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Pubmed identfication
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Classification
- Phosphatidylinositol 3-kinase subunits
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namephosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
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Synonyms gene name
- phosphoinositide-3-kinase, class 2, alpha polypeptide
- phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-05-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Phosphatidylinositol 3-kinase subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH4 clustered histone 13
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Synonyms gene
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Synonyms gene name
- H4 histone family, member K
- histone 1, H4l
- histone cluster 1, H4l
- histone cluster 1 H4 family member l
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H4 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephosphoinositide-3-kinase regulatory subunit 5
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Synonyms gene name
- phosphoinositide-3-kinase, regulatory subunit 5
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-10-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametubulin alpha 1b
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2007-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tubulins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAP2A, member of RAS oncogene family
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Classification
- RAS type GTPase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameglypican 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-08-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Glypicans
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Recording of pertinent information concerning patient's illness or illnesses.
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Tree numbers
- E05.318.308.940.968
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Qualifiersclassification, economics, legislation & jurisprudence, standards, statistics & numerical data
