PathwayReady MAP Kinase Signaling Inhibitor Panel[PathwayReady MAP Kinase Signaling Inhibitor Panel]

• Catalog number
  MBS841942
• Price
  Please ask
• Size
  NA

• Products_type
  Biochemical
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.

• Gene target
  PathwayReady   MAP   Kinase   Signaling   Inhibitor   Panel[PathwayReady   MAP   Kinase   Signaling   Inhibitor   Panel]  
• Gene symbol
  MOAP1, MAP7, MASP2, MASP1
• Short name
  PathwayReady MAP Kinase Signaling Inhibitor Panel[PathwayReady MAP Kinase Signaling Inhibitor Panel]
• Alternative name
  PathwayReady mitogen-stimulated protein kinase phosphorylation catalyst Signaling suppressor Panel[PathwayReady mitogen-stimulated protein kinase phosphorylation catalyst Signaling suppressor Panel]
• Tissue
  panel

Gene info

• Identity
  HGNC:16658
• Gene
  MOAP1
• Long gene name
  modulator of apoptosis 1
• Synonyms
  • MAP-1
  • PNMA4
• Synonyms name
  • paraneoplastic Ma antigen family member 4
• GenBank acession
  • BC015044
• Locus
  14q32.12
• Discovery year
  2002-11-13
• Entrez gene record
  64112
• Pubmed identfication
  • 11060313
• Classification
  • Paraneoplastic Ma antigens
• VEGA ID
  OTTHUMG00000169184

Gene info

• Identity
  HGNC:6869
• Gene
  MAP7
• Long gene name
  microtubule associated protein 7
• Synonyms
  • E-MAP-115
• Synonyms name
  • ensconsin
• GenBank acession
  • X73882
• Locus
  6q23.3
• Discovery year
  1999-01-22
• Entrez gene record
  9053
• Pubmed identfication
  • 8408219
• RefSeq identity
  • NM_003980
• VEGA ID
  OTTHUMG00000015646

Gene info

• Identity
  HGNC:6902
• Gene
  MASP2
• Long gene name
  MBL associated serine protease 2
• Synonyms gene
  • MASP1P1
• Synonyms gene name
  • mannan-binding lectin serine protease 2
  • mannan-binding lectin serine peptidase 1 pseudogene 1
  • mannan-binding lectin serine protease 1 pseudogene 1
• Synonyms
  • Map19
  • sMAP
  • MAP-2
• Synonyms name
  • mannose-binding lectin-associated serine protease 2
  • mannose-binding lectin associated protein 19
• GenBank acession
  • X98400
• Locus
  1p36.22
• Discovery year
  1998-12-17
• Entrez gene record
  10747
• Pubmed identfication
  • 9087411
  • 9777418
• RefSeq identity
  • NM_006610
• Classification
  • Sushi domain containing
  • Complement system activation components
• VEGA ID
  OTTHUMG00000002121
• Locus Specific Databases
  • MASP2base: Mutation registry for MASP-2 deficiency
  • LRG_82

Gene info

• Identity
  HGNC:6901
• Gene
  MASP1
• Long gene name
  MBL associated serine protease 1
• Synonyms gene
  • CRARF
  • PRSS5
• Synonyms gene name
  • mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor)
  • mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
  • mannan binding lectin serine peptidase 1
• Synonyms
  • MASP
  • Map44
  • MASP-3
  • MAP-1
• Synonyms name
  • C4/C2 activating component of Ra-reactive factor
  • mannose-binding lectin-associated serine protease 1
• GenBank acession
  • D28593
• Locus
  3q27.3
• Discovery year
  1995-07-06
• Entrez gene record
  5648
• Pubmed identfication
  • 8018603
  • 8240317
• RefSeq identity
  • NM_001879
• Classification
  • Serine proteases
  • Complement system activation components
  • Sushi domain containing
• VEGA ID
  OTTHUMG00000156461
• Locus Specific Databases
  • LRG_349

MeSH Data

• Name
  Medical Records
• Concept
  Scope note: Recording of pertinent information concerning patient's illness or illnesses.
• Tree numbers
  • E05.318.308.940.968
• Qualifiers
  classification, economics, legislation & jurisprudence, standards, statistics & numerical data

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