KLF1, 2, 4 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-9526R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  KLF1, 2, 4 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-KLF1, 2, 4 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  KLF1, 2, 4
• Specificity
  This is a highly specific antibody against KLF1, 2, 4.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  279-303/362
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLF1
• Gene ID Number
  10661
• Swiss Prot
  Q13351
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis. Is a dual regulator of fetal-to-adult globin switching. Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene. Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes. This dual activity ensures that, in most adults, fetal hemoglobin levels are low. Able to activate CD44 and AQP1 promoters. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation (By similarity).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  EKLF; INLU; CDAN4; HBFQTL6; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; KLF1
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-KLF1, 2, 4 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  KLF1  
• Gene symbol
  KLF1
• Short name
  Anti-KLF1, 2, 4
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  KLF1, 2, 4 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  Kruppel-like factor 1 (erythroid), CDAN4 and EKLF and HBFQTL6 and INLU, KLF1 and IDBG-31252 and ENSG00000105610 and 10661, metal ion binding, nuclei, Klf1 and IDBG-175231 and ENSMUSG00000054191 and 16596, KLF1 and IDBG-642908 and ENSBTAG00000006083 and 784295

Gene info

• Identity
  HGNC:6345
• Gene
  KLF1
• Long gene name
  Kruppel like factor 1
• Synonyms gene name
  • Kruppel-like factor 1 (erythroid)
• Synonyms
  • EKLF
• Synonyms name
  • erythroid Kruppel-like factor
• GenBank acession
  • U37106
• Locus
  19p13.13
• Discovery year
  1999-12-14
• Entrez gene record
  10661
• Pubmed identfication
  • 8924208
  • 9119377
• RefSeq identity
  • NM_006563
• Classification
  • Kruppel like factors
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000180536
• Locus Specific Databases
  • LRG_825

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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