Anti-MEF2A Antibody
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Catalog numberA1211-100
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PricePlease ask
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Size100 µl
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Antibody TargetMEF2A
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Target Alternative NameMEF2; Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1
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Antibody TypePolyclonal
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Species ReactivitiesHuman, Mouse, Rat
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Immunogen SequenceKLH-conjugated synthetic peptide encompassing a sequence within the center region of human MEF2A
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AccessionQ02078
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Gene Id4205
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AppearanceColorless liquid
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FormLiquid
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FormulationIn 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
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PurificationAffinity purified
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ApplicationWB
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Positive ControlWB; HEK293T, mouse muscle, rat muscle cell lysates
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Application And UsagesWB; 1:500 – 1:2000
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DescriptionTranscriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans
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HandlingThe antibody solution should be gently mixed before use
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMEF2A
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Short nameAnti-MEF2A Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibody toMEF2A (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetmyocyte enhancer factor 2A, ADCAD1 and mef2 and RSRFC4 and RSRFC9, MEF2A and IDBG-31725 and ENSG00000068305 and 4205, protein dimerization activity, nuclei, Mef2a and IDBG-192076 and ENSMUSG00000030557 and 17258, MEF2A and IDBG-628642 and ENSBTAG00000010649 and 407231
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Gene info
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Identity
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Gene
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Long gene namemyocyte enhancer factor 2A
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Synonyms
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Locus
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Discovery year1995-02-08
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Entrez gene record
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Pubmed identfication
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Classification
- Myocyte enhancer factor 2 proteins
- MADS box family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data