Z-VAD-FMK

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Cas number

187389-52-2
Chemical s molecular weight

467.49
Chemical s main applications

Z-VAD-FMK is a caspase inhibitor that inhibits apoptosis and caspase processing in Jurkat T cells treated with low concentrations of z-FA-CMK.
Chemical s category

Amines, Aromatics, Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Other name

13: PN: WO2005039629 PAGE: 18 claimed protein; 3: PN: WO0158526 SEQID: 3 claimed sequence; 3: PN: WO2011028611 SEQID: 3 unclaimed protein; Z-VAD(OMe)-FMK; Z-Val-Ala-Asp(OMe)-FMK; N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide; (5S,8S,11S)-Methyl 11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oate
Chemical s formula

C22H30FN3O7
Physical properties

No Data Available
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

No Data Available
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications

Identity

HGNC:9544
Gene

PSMB7
Long gene name

proteasome 20S subunit beta 7
Synonyms gene name
- proteasome (prosome, macropain) subunit, beta type, 7
- proteasome subunit beta 7
Synonyms
- Z
Synonyms name
- proteasome subunit β2
GenBank acession
- AJ420455
Locus

9q33.3
Discovery year

1995-11-22
Entrez gene record

5695
Pubmed identfication
- 8811196
RefSeq identity
- NM_002799
Classification
- Proteasome
VEGA ID

OTTHUMG00000021042