-
Chemical available in other sizes
Please inquire size and price
-
Stock availability
In Stock
-
Cas number
918504-65-1
-
Chemical s molecular weight
489.92
-
Chemical s main applications
Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600.
-
Chemical s category
Aromatics, Heterocycles, Protein Kinase Inhibitors and Activators, Sulfur & Selenium Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
-
Other name
N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide; PLX 4032; RG 7204; Ro 51-85426;
-
Chemical s formula
C23H18ClF2N3O3S
-
Physical properties
Off-White Solid
-
Melting temperature
>263ºC (dec.)
-
Boiling temperature
No Data Available
-
Chemical s soluble in
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
-
Stability conditions
No Data Available
-
Storage
Refrigerator
-
