TC ASK 10

• Catalog number
  T012000
• Price
  Please ask
• Size
  5 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  In Stock
• Cas number
  1005775-56-3
• Chemical s molecular weight
  432.35
• Chemical s main applications
  TC ASK 10 is a potent ASK1 inhibitor. It displays selectivity for ASK1 over other kinases including ASK2, MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf. It blocks downstream JNK1/p38 phosphorylation in cells.
• Chemical s category
  Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
• Other name
  4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]-,benzamide Dihydrochloride; 4-tert-Butyl-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide Dihydrochloride
• Chemical s formula
  C21H23Cl2N5O
• Physical properties
  White to Off-White Solid
• Melting temperature
  >270° (dec.)
• Boiling temperature
  No Data Available
• Chemical s soluble in
  DMSO (Slightly), Methanol (Slightly)
• Stability conditions
  No Data Available
• Storage
  Refrigerator, under inert atmosphere
• Chemical s specifications

• Gene target
  ASK  
• Gene symbol
  DBF4
• Short name
  TC ASK 10
• Alternative name
  TC ASK 10

Gene info

• Identity
  HGNC:17364
• Gene
  DBF4
• Long gene name
  DBF4 zinc finger
• Synonyms gene name
  • DBF4 homolog (S. cerevisiae)
• Synonyms
  • ASK
  • chif
  • ZDBF1
  • DBF4A
• Synonyms name
  • activator of S phase kinase
  • chiffon homolog (Drosophila)
  • zinc finger, DBF-type containing 1
  • DBF4 zinc finger A
• GenBank acession
  • AF160876
• Locus
  7q21.12
• Discovery year
  2005-11-15
• Entrez gene record
  10926
• Pubmed identfication
  • 10373557
  • 10517317
• RefSeq identity
  • NM_006716
• Classification
  • Zinc fingers DBF-type
• VEGA ID
  OTTHUMG00000131034

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