Sofosbuvir 3',5'-Bis-(S)-phosphate
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Catalog number
S675605
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Price
Please ask
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Size
25 mg
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Chemical available in other sizes
Please inquire size and price
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Stock availability
Please Inquire
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Cas number
1337482-17-3
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Chemical s molecular weight
798.69
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Chemical s main applications
Sofosbuvir 3',5'-Bis-(S)-phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
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Chemical s category
Heterocycles, Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name
(2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((R)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate
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Chemical s formula
C34H45FN4O13P2
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Physical properties
No Data Available
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Melting temperature
No Data Available
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Boiling temperature
No Data Available
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Chemical s soluble in
No Data Available
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Stability conditions
No Data Available
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Storage
No Data Available
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Gene target
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Short name
Sofosbuvir 3',5'-Bis-(S)-phosphate
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Alternative name
Sofosbuvir 3',5'-Bis-(S)-phosphate
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