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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
1092538-80-1
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Chemical s molecular weight
358.39
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Chemical s main applications
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD.
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Chemical s category
Amines, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name
2-Amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 2-Amino-1-ethyl-1,4-dihydro-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide
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Chemical s formula
C18H22N4O4
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Physical properties
White to Pale Yellow Solid
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Melting temperature
>206°C (dec.)
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Boiling temperature
No Data Available
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Chemical s soluble in
DMSO (Slightly)
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Stability conditions
No Data Available
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Storage
Refrigerator
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