(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

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Stock availability

In Stock
Cas number

77521-29-0
Chemical s molecular weight

186.17
Chemical s main applications

A potent and selective agonist of the putative, excitatory neurotransmitter L-glutamic acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists.
Chemical s category

Heterocycles, Neurochemicals
Other name

D,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid; AMPA; D,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid; γ-Amino-3-hydroxy-5-methylisoxazole-4-propionic Αcid;
Chemical s formula

C7H10N2O4
Physical properties

White to Off-White Solid
Melting temperature

>162°C (dec.)
Boiling temperature

No Data Available
Chemical s soluble in

Water
Stability conditions

Store in freezer at -20°C
Storage

-20°C Freezer
Chemical s specifications
Description

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,

Gene target

α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Gene symbol

TRP-TGG3-5, TRK-TTT3-5, TRI-AAT5-3, HS3ST5, TRP-TGG3-4, TRK-TTT3-4, TSPAN5, TRY-GTA5-5, NTF4
Short name

(R S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Alternative name

(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

Identity

HGNC:34847
Gene

TRP-TGG3-5
Long gene name

tRNA-Pro (anticodon TGG) 3-5
Synonyms gene
- TRNAP16
- TRP-TGG3-4
Synonyms gene name
- transfer RNA proline 16 (anticodon UGG)
- transfer RNA-Pro (TGG) 3-4
- transfer RNA-Pro (TGG) 3-5
Synonyms
- tRNA-Pro-TGG-3-5
GenBank acession
- HG984000
Locus

16p13.3
Discovery year

2008-08-29
Entrez gene record

100189281
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34877
Gene

TRI-AAT5-3
Long gene name

tRNA-Ile (anticodon AAT) 5-3
Synonyms gene
- TRNAI17
- TRI-AAT5-5
Synonyms gene name
- transfer RNA isoleucine 17 (anticodon AAU)
- transfer RNA-Ile (AAT) 5-5
- transfer RNA-Ile (AAT) 5-3
Synonyms
- tRNA-Ile-AAT-5-3
GenBank acession
- HG983851
Locus

6p22.1
Discovery year

2008-08-29
Entrez gene record

100189310
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34956
Gene

TRP-TGG3-4
Long gene name

tRNA-Pro (anticodon TGG) 3-4
Synonyms gene
- TRNAP21
- TRP-TGG3-3
Synonyms gene name
- transfer RNA proline 21 (anticodon UGG)
- transfer RNA-Pro (TGG) 3-3
- transfer RNA-Pro (TGG) 3-4
Synonyms
- tRNA-Pro-TGG-3-4
GenBank acession
- HG983999
Locus

16p13.3
Discovery year

2008-08-29
Entrez gene record

100189388
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:33256
Gene

TRK-TTT3-4
Long gene name

tRNA-Lys (anticodon TTT) 3-4
Synonyms gene
- TRNAK3
- TRK-TTT3-3
Synonyms gene name
- transfer RNA lysine 3 (anticodon UUU)
- transfer RNA-Lys (TTT) 3-3
- transfer RNA-Lys (TTT) 3-4
Synonyms
- tRNA-Lys-TTT-3-4
GenBank acession
- HG983933
Locus

11q12.1
Discovery year

2007-02-01
Entrez gene record

100049613
Pubmed identfication
- 3678837
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34558
Gene

TRY-GTA5-5
Long gene name

tRNA-Tyr (anticodon GTA) 5-5
Synonyms gene
- TRNAY3
- TRY-GTA5-3
Synonyms gene name
- transfer RNA tyrosine 3 (anticodon GUA)
- transfer RNA-Tyr (GTA) 5-3
- transfer RNA-Tyr (GTA) 5-5
Synonyms
- tRNA-Tyr-GTA-5-5
GenBank acession
- HG984080
Locus

14q11.2
Discovery year

2008-08-29
Entrez gene record

100189001
Classification
- Cytoplasmic transfer RNAs