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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
149-29-1
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Chemical s molecular weight
154.12
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Chemical s main applications
Patulin (PAT), a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys, is mainly found in ripe apple and apple products. Patulin-induced genotoxicity and modulation of glutathione in Hep G2 cells. Patulin is an antibiotic. Patulin-induced nephropathy and gastrointestinal tract malfunction have been demonstrated in several animal models. The oral LD50 value of patulin ranges between 29 and 55 mg/kg body weight in rodents and 170 mg/kg body weight in poultry. The World Health Organization considers patulin cytotoxic and established a safety level of patulin in apple juice at 50 μM. At 100-200 μM, patulin can directly increase intracellular oxidative stress in HEK293 and HL-60 cells. In 1944, this compound was tested in a clinical trial for potential antibiotic properties to treat the common cold.
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Chemical s category
Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name
4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one; Clairformin; Clavacin; Clavatin; Claviformin; DL-Patulin; Expansin; Expansine; Mycoin; Mycoin C; Mycoin C3; NSC 32951; NSC 8120; Patuline; Penicidin; Terinin;
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Chemical s formula
C7H6O4
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Physical properties
Off-White to Pale Orange Solid
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Melting temperature
103-107°C
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Boiling temperature
No Data Available
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Chemical s soluble in
Acetone (Slightly), Methanol (Slightly, Heated)
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Stability conditions
No Data Available
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Storage
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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