N,N’-Di-Boc-S-di(trityl)-di-O-cysteinyl-glycinoyl Curcumin
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Catalog numberD420025
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PricePlease ask
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Size1 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityPending QC
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Cas numberThis product doesn't have CAS Number
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Chemical s molecular weight1373.63
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Chemical s main applicationsN,N’-Di-boc-S-di(trityl)-di-O-cysteinyl-glycinoyl Curcumin is an intermediate of Di-O-cysteinyl-glycinoyl Curcumin (D455600). Di-O-cysteinyl-glycinoyl curcumin is a metabolite of curcumin (C838500), which is a natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers disease (Chem. and Eng. News 90(31), 44 (2012)).
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Other name4-((1E,6E)-7-(4-(2-((R)-2-((Tert-butoxycarbonyl)amino)-3-(tritylthio)propanamido)acetoxy)-3-methoxyphenyl)-3,5-dioxohepta-1,6-dien-1-yl)-2-methoxyphenyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-(tritylthio)propanamido)acetate
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Chemical s formulaC79H80N4O14S2
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Physical propertiesNo Data Available
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Melting temperatureNo Data Available
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Boiling temperatureNo Data Available
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Chemical s soluble inChloroform, Ethyl Acetate
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Stability conditionsNo Data Available
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StorageNo Data Available
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Gene target
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Gene symbolH2BC19P, CENPO, H4C15, B3GAT2, POFUT1, CTSL3P, HLA-S, SDR9C7, GNAO1, STRN3
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Short nameN N’-Di-Boc-S-di(trityl)-di-O-cysteinyl-glycinoyl Curcumin
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Alternative nameN,N’-Di-Boc homolog (mouse)-S-di(trityl)-di-O-cysteinyl-glycinoyl Curcumin
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Alternative to gene targetBoc homolog (mouse), BOC and IDBG-50192 and ENSG00000144857 and 91653, protein binding, Plasma membranes, Boc and IDBG-162156 and ENSMUSG00000022687 and 117606, BOC and IDBG-632359 and ENSBTAG00000013909 and 512018
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Gene info
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Identity
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Gene
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Long gene nameH2B clustered histone 19, pseudogene
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Synonyms gene
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Synonyms gene name
- histone 2, H2bd
- H2B histone family, member O
- histone cluster 2, H2bd (pseudogene)
- histone cluster 2 H2B family member d (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-02-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H2B histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecentromere protein O
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-06-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Constitutive centromere associated network
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH4 clustered histone 15
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Synonyms gene
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Synonyms gene name
- histone 2, H4b
- histone cluster 2, H4b
- histone cluster 2 H4 family member b
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H4 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namebeta-1,3-glucuronyltransferase 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-01-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Beta-1,3-glucuronyltransferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein O-fucosyltransferase 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-10-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- Fucosyltransferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecathepsin L family member 3, pseudogene
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Synonyms gene
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Synonyms gene name
- cathepsin L family member 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-04-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class I, S (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-10-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameshort chain dehydrogenase/reductase family 9C member 7
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Synonyms gene name
- short chain dehydrogenase/reductase family 9C, member 7
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-12-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Short chain dehydrogenase/reductase superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameG protein subunit alpha o1
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Synonyms gene name
- guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
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Synonyms
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Locus
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Discovery year1988-04-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G protein subunits alpha, group i
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namestriatin 3
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Synonyms gene name
- striatin, calmodulin binding protein 3
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Synonyms
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Synonyms name
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Locus
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Discovery year2002-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
- STRIPAK complex
- Protein phosphatase 2 regulatory subunits
- MicroRNA protein coding host genes
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VEGA ID
