MM-419447-d4 TFA Salt (Linaclotide Metabolite)

• Catalog number
  M425462
• Price
  Please ask
• Size
  1 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  In Stock
• Cas number
  This product doesn't have CAS Number
• Chemical s molecular weight
  1373.5811402
• Chemical s main applications
  MM-419447-d4 TFA Salt, is a labelled analogue of MM-419447 (M425460), a Linaclotide metabolite, which is a guanylate cyclase-C agonist currently being studied in Phase 3 trials for the treatment of irritable bowel syndrome with constipation.
• Other name
  L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteine-d4 TFA Salt; 132: PN: US20050020811 SEQID: 125 Claimed Sequence-d4 TFA Salt; 13: PN: WO2014151200 SEQID: 56 Claimed Protein-d4 TFA Salt; 44: PN: US20120237593 SEQID: 56 Claimed Sequence-d4 TFA Salt; 5: PN: WO2016015055 SEQID: 6 Claimed Sequence-d4 TFA Salt; 652: PN: WO2007022531 PAGE: 248 Claimed Protein-d4 TFA Salt; 65: PN: WO2005087797 SEQID: 71 Unclaimed Sequence-d4 TFA Salt; 78: PN: US20090062207 SEQID: 81 Unclaimed Protein-d4; 80: PN: US20060281682 SEQID: 81 Claimed Protein-d4 TFA Salt; 81: PN: US20060258593 SEQID: 81 Unclaimed Protein-d4 TFA Salt; 90: PN: WO2008106429 PAGE: 4/64 Unclaimed Protein-d4 TFA Salt; 9: PN: WO2010027405 SEQID: 9 Claimed Protein-d4 TFA Salt;
• Chemical s formula
  C50H72D4N14O19S6 •C2HF3O2
• Physical properties
  White to Off-White Solid
• Melting temperature
  >250°C (dec.)
• Boiling temperature
  No Data Available
• Chemical s soluble in
  Water (Slightly)
• Stability conditions
  No Data Available
• Storage
  Refrigerator
• Chemical s specifications

• Gene target
  MM-419447-d4   TFA   Salt   Linaclotide   Metabolite  
• Gene symbol
  PFDN5, TMEM243
• Short name
  MM-419447-d4 TFA Salt (Linaclotide Metabolite)
• Alternative name
  millimeter-419447-d4 TFA Salt (Linaclotide Metabolite)

Gene info

• Identity
  HGNC:8869
• Gene
  PFDN5
• Long gene name
  prefoldin subunit 5
• Synonyms gene name
  • prefoldin 5
• Synonyms
  • PFD5
  • MM-1
• GenBank acession
  • D89667
• Locus
  12q13.13
• Discovery year
  1998-08-06
• Entrez gene record
  5204
• Pubmed identfication
  • 9630229
  • 9792694
• Classification
  • Prefoldin subunits
• VEGA ID
  OTTHUMG00000169675

Gene info

• Identity
  HGNC:21707
• Gene
  TMEM243
• Long gene name
  transmembrane protein 243
• Synonyms gene
  • C7orf23
• Synonyms gene name
  • chromosome 7 open reading frame 23
  • transmembrane protein 243, mitochondrial
• Synonyms
  • MGC4175
  • MM-TRAG
• Synonyms name
  • MDR1 and mitochondrial taxol resistance associated gene
• Locus
  7q21.12
• Discovery year
  2003-07-14
• Entrez gene record
  79161
• RefSeq identity
  • NM_024315
• VEGA ID
  OTTHUMG00000130823

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