LEE011 Succinate

• Catalog number
  L321000
• Price
  Please ask
• Size
  2,5 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  In Stock
• Cas number
  1374639-75-4
• Chemical s molecular weight
  552.63
• Chemical s main applications
  LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models.
• Chemical s category
  Amines, Aromatics, Heterocycles, Inhibitors
• Other name
  7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide Succinate
• Chemical s formula
  C27H36N8O5
• Physical properties
  Pale Beige Solid
• Melting temperature
  >160ºC (dec.)
• Boiling temperature
  No Data Available
• Chemical s soluble in
  DMSO (Slightly), Methanol (Slightly)
• Stability conditions
  No Data Available
• Storage
  Refrigerator
• Chemical s specifications

• Gene target
  LEE011   Succinate  
• Short name
  LEE011 Succinate
• Alternative name
  LEE011 Succinate

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