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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
109944-15-2
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Chemical s molecular weight
232.19
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Chemical s main applications
Kifunensine is an alkaloid produced by the fungus, Kitasatosporia kifunense, and has been shown to be a weak inhibitor of aryl mannosidase. It is a unique oxamide derivative of mannojirimycin and a potent inhibitor of the glycoprotein processing enzyme mannosidase I. Kifunenesine is ineffective in inhibiting either mannosidase II or the endoplasmic reticulum (ER) a-mannosidase. It also possesses immunomodulating properties based on chemical, physicochemical and x-ray crystallographic analysis. When tested in cell culture using influenza virus-infected MDCK cells, kifunensine, at 1 mg/ml or less, caused almost complete inhibition of complex chain formation with the accumulation of Man9(GlcNAc)2. Thus, kifunensine was proven to be 50 to 100 times more effective than deoxymannojirimycin. Physicochemical characteristics: Kifunensine is soluble in hot water. Solutions should be made immediately prior to use. The compound should be dessicated and stored at -20 deg C.
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Chemical s category
Inhibitors, Glycosidase Inhibitors,
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Other name
[5R-(5α,6β,7α,8α,8aα)]-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione; (+)-Kifunensine; FR 900494
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Chemical s formula
C8H12N2O6
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Physical properties
White Solid
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Melting temperature
>280°C (dec.)
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Boiling temperature
No Data Available
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Chemical s soluble in
DMSO (Slightly), Water (Slightly, Heated)
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Stability conditions
Desiccate and Store at -20°C
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Storage
-20°C Freezer
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