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Chemical available in other sizes
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Stock availability
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Cas number
202475-60-3
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Chemical s molecular weight
297.31
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Chemical s main applications
Janex 1 is a Janus tyrosine kinase 3 (JAK3) inhibitor. Inhibition of JAK3 has been shown to exhibit protective action against the development of T1D in non-obese diabetic (NOD) mice. Janex 1 has been shown to suppresses proliferation of short-term cultured NOD CD4+ T cells through induction of apoptosis, while promoting survival of a particular population of long-term cultured cells. It ameliorates the expression of TNF-α-induced cell adhesion molecules and improves myocardial vascular permeability.
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Chemical s category
Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name
4-(4'-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline; WHI-P 131
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Chemical s formula
C16H15N3O3
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Physical properties
No Data Available
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Melting temperature
No Data Available
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Boiling temperature
No Data Available
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Chemical s soluble in
No Data Available
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Stability conditions
No Data Available
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Storage
No Data Available
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