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Chemical available in other sizes
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Stock availability
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Cas number
1146963-51-0
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Chemical s molecular weight
350.33
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Chemical s main applications
J 147 is a novel neurotrophic drug for cognitive enhancement and Alzheimer's disease. J 147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer's disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques.
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Chemical s category
Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name
2,2,2-Trifluoroacetic Acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl) methylene]hydrazide;
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Chemical s formula
C18H17F3N2O2
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Physical properties
No Data Available
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Melting temperature
No Data Available
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Boiling temperature
No Data Available
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Chemical s soluble in
No Data Available
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Stability conditions
No Data Available
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Storage
No Data Available
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