H-1152 Glycyl Dihydrochloride

Chemical available in other sizes

Please inquire size and price
Stock availability

In Stock
Cas number

913844-45-8
Chemical s molecular weight

449.4
Chemical s main applications

A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis.
Chemical s category

Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Other name

2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride; (2S)-4-(Aminoacetyl)hexahydro -2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride;
Chemical s formula

C18H26Cl2N4O3S
Physical properties

Pale-Yellow to Pale Beige Solid
Melting temperature

>190°C (dec.)
Boiling temperature

No Data Available
Chemical s soluble in

Methanol (Slightly), Water (Slightly)
Stability conditions

Hygroscopic
Storage

Hygroscopic, -20°C Freezer, Under inert atmosphere
Chemical s specifications

Gene target

H-1152 Glycyl Dihydrochloride
Gene symbol

NCAPH, HLA-H, IGHV3-69-1, FUT1, PIGH, NEFH, HFE, RAB11B, ATCAY, RAB35
Short name

H-1152 Glycyl Dihydrochloride
Alternative name

H-1152 Glycyl Dihydrochloride

Identity

HGNC:1112
Gene

NCAPH
Long gene name

non-SMC condensin I complex subunit H
Synonyms gene
- BRRN1
Synonyms gene name
- barren (Drosophila) homolog
- barren homolog (Drosophila)
- barren homolog 1 (Drosophila)
- non-SMC condensin I complex, subunit H
Synonyms
- CAP-H
- hCAP-H
GenBank acession
- BC024211
Locus

2q11.2
Discovery year

1998-02-11
Entrez gene record

23397
Pubmed identfication
- 9417923
RefSeq identity
- NM_015341
Classification
- Condensin I subunits
- Kleisins
VEGA ID

OTTHUMG00000130451

Identity

HGNC:5631
Gene

IGHV3-69-1
Long gene name

immunoglobulin heavy variable 3-69-1 (pseudogene)
Synonyms gene
- IGHV3-H
Synonyms gene name
- immunoglobulin heavy variable 3-H (provisional)
- immunoglobulin heavy variable 3-H pseudogene (provisional)
- immunoglobulin heavy variable 3-H (pseudogene)
Synonyms
- IGHV3-h
GenBank acession
- AJ879484
Locus

14q32.33
Discovery year

2000-04-04
Entrez gene record

28402
Pubmed identfication
- 16133446
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000191145

Identity

HGNC:4012
Gene

FUT1
Long gene name

fucosyltransferase 1 (H blood group)
Synonyms gene
- H
- HSC
Synonyms gene name
- fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, Bombay phenotype included)
- fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase)
Synonyms name
- galactoside 2-alpha-L-fucosyltransferase
Locus

19q13.33
Discovery year

1989-06-06
Entrez gene record

2523
RefSeq identity
- NM_000148
Classification
- Fucosyltransferases
- Blood group antigens
VEGA ID

OTTHUMG00000183325
Locus Specific Databases
- Blood Group Antigen Mutation Database
- LRG_810

Identity

HGNC:7737
Gene

NEFH
Long gene name

neurofilament heavy chain
Synonyms gene name
- neurofilament, heavy polypeptide 200kDa
- neurofilament heavy polypeptide
- neurofilament heavy
Synonyms
- NF-H
- NFH
Locus

22q12.2
Discovery year

1988-08-31
Entrez gene record

4744
RefSeq identity
- NM_021076
Classification
- Intermediate filaments Type IV
VEGA ID

OTTHUMG00000151155
Locus Specific Databases
- ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Identity

HGNC:4886
Gene

HFE
Long gene name

homeostatic iron regulator
Synonyms gene name
- hemochromatosis
Synonyms
- HLA-H
- HFE1
Synonyms name
- high Fe
Locus

6p22.2
Discovery year

1986-01-01
Entrez gene record

3077
Pubmed identfication
- 3460331
- 28474781
- 9054933
Classification
- C1-set domain containing
VEGA ID

OTTHUMG00000016348
Locus Specific Databases
- ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database
- LRG_748