Defluoro-MDV 3100 (Defluoro-enzalutamide)

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Cas number

915087-16-0
Chemical s molecular weight

446.45
Chemical s main applications

Defluoro-MDV 3100 (Defluoro-enzalutamide) is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer.
Other name

4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-N-methylbenzamide; 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide;
Chemical s formula

C21H17F3N4O2S
Physical properties

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Melting temperature

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Boiling temperature

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Chemical s soluble in

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Chemical s specifications