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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
179324-69-7
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Chemical s molecular weight
384.24
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Chemical s main applications
Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
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Chemical s category
Chiral Reagents, Boron Derivatives, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
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Other name
B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; Velcade; Radiciol; NSC 681239; DPBA; LDP 341; MG 341; MLN 341; NSC 681239; PS 314; PS 341; Radiciol; Velcade;
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Chemical s formula
C19H25BN4O4
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Physical properties
White to Off-White Solid
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Melting temperature
>122°C (dec.)
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Boiling temperature
N/A
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Chemical s soluble in
Chloroform (Slightly), Methanol (Slightly)
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Stability conditions
Hygroscopic and Moisture Sensitive
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Storage
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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