Boc-cis-3-hydroxy-L-proline

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Stock availability

Available in 2-3 weeks
Cas number

186132-96-7
Chemical s molecular weight

231.25
Chemical s main applications

Boc-cis-3-hydroxy-L-proline is used to prepare analogs of cyclothialidine, a DNA-gyrase inhibitor with antibacterial activities. It is also used to synthesize potent 3- or 4-substituted-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors.
Chemical s category

Amines, Chiral Reagents, Heterocycles
Other name

(2S-cis)-3-Hydroxy-1,2-pyrrolidinedicarboxylic acid 1-(1,1-Dimethylethyl) Ester; (2S,3R)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic Acid; (2S,3R)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic Acid
Chemical s formula

C10H17NO5
Physical properties

No Data Available
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

No Data Available
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications

Gene target

Boc-cis-3-hydroxy-L-proline
Gene symbol

L3MBTL2, CPT1A, POM121L2, CLDN10, RPL32P1, FABP1, COX7A2, NFIA, JAK3, ATRN
Short name

Boc-cis-3-hydroxy-L-proline
Alternative name

Boc homolog (mouse)-cis-3-hydroxy-L-proline
Alternative to gene target

Boc homolog (mouse), BOC and IDBG-50192 and ENSG00000144857 and 91653, protein binding, Plasma membranes, Boc and IDBG-162156 and ENSMUSG00000022687 and 117606, BOC and IDBG-632359 and ENSBTAG00000013909 and 512018

Identity

HGNC:18594
Gene

L3MBTL2
Long gene name

L3MBTL histone methyl-lysine binding protein 2
Synonyms gene name
- l(3)mbt-like 2 (Drosophila)
- L3MBTL2, polycomb repressive complex 1 subunit
Synonyms
GenBank acession
- AJ305226
Locus

22q13.2
Discovery year

2002-04-29
Entrez gene record

83746
Pubmed identfication
- 11682070
- 21596310
RefSeq identity
- NM_031488
Classification
- MBT domain containing
VEGA ID

OTTHUMG00000150942

Identity

HGNC:13973
Gene

POM121L2
Long gene name

POM121 transmembrane nucleoporin like 2
Synonyms gene name
- POM121 membrane glycoprotein-like 2 (rat)
- POM121 membrane glycoprotein-like 2
- POM121 transmembrane nucleoporin-like 2
Synonyms
- POM121-L
GenBank acession
- AL021808
Locus

6p22.1
Discovery year

2001-07-20
Entrez gene record

94026
RefSeq identity
- NM_033482
VEGA ID

OTTHUMG00000014475

Identity

HGNC:6193
Gene

JAK3
Long gene name

Janus kinase 3
Synonyms
- L-JAK
- JAKL
- LJAK
- JAK3_HUMAN
- JAK-3
Synonyms name
- tyrosine-protein kinase JAK3
- leukocyte Janus kinase
GenBank acession
- U31601
Locus

19p13.11
Discovery year

1994-12-19
Entrez gene record

3718
Pubmed identfication
- 8921370
- 9226382
RefSeq identity
- NM_000215
Classification
- Jak family tyrosine kinases
VEGA ID

OTTHUMG00000165648
Locus Specific Databases
- JAK3base: Mutation registry for autosomal recessive severe combined JAK3 deficiency
- LRG_77