-
Chemical available in other sizes
Please inquire size and price
-
Stock availability
Pending QC
-
Cas number
2482-00-0
-
Chemical s molecular weight
228.27
-
Chemical s main applications
General Uses: Neuroprotective, CNS studies, Autism and depression research Description: Agmatine Sulfate is a polyamine derived from L-arginine (A769500) decarboxylation and is a known putative endogenous neurotransmitter at imidazoline receptors. Agmatine sulfate displaces clonidine at α2-adrenergic and at imidazoline receptors and was recently shown to exert some neuroprotective effects. It blocks NMDA-receptor associated cation channels. Acts as a competitive inhibitor of nitric oxide synthase (NOS). It functions as neurotransmitter since it is stored in synaptic vesicles and is related from axon terminals by depolarization(1). Protects autistic behavior in rats (2) and reverses depressive like behavior in mice. (3)
-
Chemical s category
Amines, Amino Acids & Derivatives, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
-
Other name
N-(4-aminobutyl)guanidine Sulfate; NIH 11035
-
Chemical s formula
C5H16N4O4S
-
Physical properties
White Solid
-
Melting temperature
231-233°C
-
Boiling temperature
No Data Available
-
Chemical s soluble in
Water
-
Stability conditions
No Data Available
-
Storage
Room Temp
-