7-O-Desmethoxy-7-O-chloroethyl Erlotinib Hydrochloride

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Cas number

183320-19-6
Chemical s molecular weight

434.32
Chemical s main applications

7-O-Desmethoxy-7-O-chloroethyl Erlotinib hydrochloride is a derivative of Erlotinib (E625000), an epidermal growth factor receptor inhibitor and tyrosine kinase inhibitor that is used to treat patients with lung cancer.
Chemical s category

Amines, Aromatics, Drug Analogues, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors
Other name

7-(2-Chloroethoxy)-N-(3-ethynylphenyl)-6-(2-methoxyethoxy)-4-quinazolinamine Hydrochloride (1:1); 7-(2-Chloroethoxy)-N-(3-ethynylphenyl)-6-(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride
Chemical s formula

C21H21Cl2N3O3
Physical properties

No Data Available
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

No Data Available
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications

Gene target

7-O-Desmethoxy-7-O-chloroethyl Erlotinib Hydrochloride
Gene symbol

CENPO, H4C15, POFUT1, PIRC34, PIRC33, PIRC32, SNORD114-7, IGHV3OR15-7, SNORD115-7, RNU6-7
Short name

7-O-Desmethoxy-7-O-chloroethyl Erlotinib Hydrochloride
Alternative name

7-O-Desmethoxy-7-O-chloroethyl Erlotinib Hydrochloride

Identity

HGNC:29607
Gene

H4C15
Long gene name

H4 clustered histone 15
Synonyms gene
- HIST2H4B
Synonyms gene name
- histone 2, H4b
- histone cluster 2, H4b
- histone cluster 2 H4 family member b
Synonyms
- H4/o
GenBank acession
- BC108260
Locus

1q21.2
Discovery year

2006-06-12
Entrez gene record

554313
Pubmed identfication
- 15527963
RefSeq identity
- NM_001034077
Classification
- H4 histones
VEGA ID

OTTHUMG00000188201

Identity

HGNC:14988
Gene

POFUT1
Long gene name

protein O-fucosyltransferase 1
Synonyms
- O-FUT
- O-Fuc-T
- KIAA0180
- FUT12
Synonyms name
- peptide-O-fucosyltransferase
- GDP-fucose protein O-fucosyltransferase 1
GenBank acession
- AF375884
Locus

20q11.21
Discovery year

2001-10-29
Entrez gene record

23509
Pubmed identfication
- 9023546
- 9525914
RefSeq identity
- NM_015352
Classification
- MicroRNA protein coding host genes
- Fucosyltransferases
VEGA ID

OTTHUMG00000133268

Identity

HGNC:5633
Gene

IGHV3OR15-7
Long gene name

immunoglobulin heavy variable 3/OR15-7 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable 3/OR15-7
- immunoglobulin heavy variable 3/OR15-7 pseudogene
Synonyms
- IGHV3/OR15-7
GenBank acession
- Z29597
Locus

15q11.2
Discovery year

2000-04-17
Entrez gene record

28318
Classification
- Immunoglobulin heavy (IGH) orphons
VEGA ID

OTTHUMG00000171835