6-N-[4,5-Dimethyl-thiazol-2-yl]-aminopyridazine 3-Carboxylic Acid

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Cas number

1275449-43-8
Chemical s molecular weight

250.28
Chemical s main applications

6-N-[4,5-Dimethyl-thiazol-2-yl]-aminopyridazine 3-Carboxylic Acid is prepared from 3-Chloro-6-methylpyridazine (C365550). 3-Chloro-6-methylpyridazine is used for preparation of heterocyclic compounds as integrase inhibiting antiviral agents.
Chemical s category

Amines, Aromatics, Heterocycles
Other name

6-[(4,5-Dimethyl-2-thiazolyl)amino]-3-pyridazinecarboxylic Acid
Chemical s formula

C10H10N4O2S
Physical properties

No Data Available
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

No Data Available
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications

Gene target

6-N 5-Dimethyl-thiazol-2-yl] aminopyridazine 3-Carboxylic Acid
Gene symbol

GH1, H2BC17, POLM, NRAS, SDC3, PIGN, WASL, MAP6, HLA-N, FERD3L
Short name

6-N-[4 5-Dimethyl-thiazol-2-yl]-aminopyridazine 3-Carboxylic Acid
Alternative name

6-N-[4,5-Dimethyl-thiazol-2-yl]-aminopyridazine 3-Carboxylic Acid

Identity

HGNC:4758
Gene

H2BC17
Long gene name

H2B clustered histone 17
Synonyms gene
- H2BFN
- HIST1H2BO
Synonyms gene name
- H2B histone family, member N
- histone 1, H2bo
- histone cluster 1, H2bo
- histone cluster 1 H2B family member o
Synonyms
- H2B/n
- H2B.2
GenBank acession
- X57138
Locus

6p22.1
Discovery year

1998-08-27
Entrez gene record

8348
Pubmed identfication
- 1768865
- 12408966
RefSeq identity
- NM_003527
Classification
- H2B histones
VEGA ID

OTTHUMG00000014493

Identity

HGNC:7989
Gene

NRAS
Long gene name

NRAS proto-oncogene, GTPase
Synonyms gene name
- neuroblastoma RAS viral (v-ras) oncogene homolog
- neuroblastoma RAS viral oncogene homolog
Synonyms
- N-ras
GenBank acession
- BC005219
Locus

1p13.2
Discovery year

2001-06-22
Entrez gene record

4893
Pubmed identfication
- 6705568
- 11524732
RefSeq identity
- NM_002524
Classification
- RAS type GTPase family
VEGA ID

OTTHUMG00000012059
Locus Specific Databases
- NRASbase: Mutation registry for autoimmune lymphoproliferative syndrome type IV
- LRG_92

Identity

HGNC:12735
Gene

WASL
Long gene name

WASP like actin nucleation promoting factor
Synonyms gene name
- Wiskott-Aldrich syndrome-like
- Wiskott-Aldrich syndrome like
Synonyms
- N-WASP
- NWASP
- WASPB
GenBank acession
- D88460
Locus

7q31.32
Discovery year

1998-10-14
Entrez gene record

8976
Pubmed identfication
- 9422512
- 9322739
- 23527602
RefSeq identity
- NM_003941
Classification
- Wiskott-Aldrich Syndrome protein family
VEGA ID

OTTHUMG00000157346

Identity

HGNC:16660
Gene

FERD3L
Long gene name

Fer3 like bHLH transcription factor
Synonyms gene name
- Fer3-like (Drosophila)
- Fer3-like bHLH transcription factor
Synonyms
- NATO3
- N-TWIST
- bHLHa31
GenBank acession
- AF369897
Locus

7p21.1
Discovery year

2002-12-09
Entrez gene record

222894
Pubmed identfication
- 11472856
- 12217327
Classification
- Basic helix-loop-helix proteins
VEGA ID

OTTHUMG00000090823