(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide-d2
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Catalog numberD446992
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PricePlease ask
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Size0,5 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityPlease Inquire
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Cas numberThis product doesn't have CAS Number
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Chemical s molecular weight513.53
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Chemical s main applications(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide-d2 is an isotope labelled intermediate of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor.
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Chemical s formulaC27H21D4F2N3O5
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Physical propertiesPale Yellow Solid
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Melting temperature149-152°C
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Boiling temperatureNo Data Available
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Chemical s soluble inDMSO (Slightly), Methanol (Slightly, Heated)
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Stability conditionsNo Data Available
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StorageHygroscopic, -20°C Freezer, Under inert atmosphere
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DescriptionA methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
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Gene target
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Gene symbolTRC-GCA9-4, RNU6-9, PIRC45, PIRC47, PIRC38, PIRC43
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Short name(4R 12aS)-N-[(2 4-Difluorophenyl)methyl]-3 4 6 8 12 12a-hexahydro-4-methyl-6 8-dioxo-7-(phenylmethoxy)-2H-pyrido[1',2':4 5]pyrazino[2 1-b][1 3]oxazine-9-carboxamide-d2
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Alternative name(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide-d2
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Gene info
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Identity
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Gene
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Long gene nametRNA-Cys (anticodon GCA) 9-4
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Synonyms gene
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Synonyms gene name
- transfer RNA cysteine 27 (anticodon GCA)
- transfer RNA-Cys (GCA) 9-4
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nameRNA, U6 small nuclear 9
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Synonyms
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Locus
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Discovery year2008-06-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nuclear RNAs
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 45
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 47
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 38
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 43
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters