2,3,4,5-Tetrahydro-7-methoxy-4-(methyl-d3)-1,4-benzothiazepine

• Catalog number
  T293862
• Price
  Please ask
• Size
  5 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Please Inquire
• Cas number
  1167435-22-4
• Chemical s molecular weight
  212.33
• Chemical s main applications
  t is a labelled benzothiazepine derivative that binds the RyR1 channel and enhances the binding affinity of Calstabin-1. By preventing the depletion of Calstabin-1 from the RyR1 complex, S 107 slows muscle fatique and reduces muscle damage in exercised mice. In a murine model of Duchenne muscular dystrophy, S 107 reduces biochemical and histological evidence of the muscle damage associated with muscular dystrophy, improves muscle function, and increases exercise performance.
• Chemical s category
  Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Other name
  S 107-d3;
• Chemical s formula
  C11H12D3NOS
• Physical properties
  No Data Available
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  No Data Available
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications
• Description
  A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,

• Gene target
  5-Tetrahydro-7-methoxy-4   methyl-d3   4-benzothiazepine  
• Gene symbol
  PIRC34, PIRC33, PIRC32, SNORD114-7, IGHV3OR15-7, SNORD115-7, RNU6-7, PIRC29, PIRC30, PIRC31
• Short name
  2 3 4 5-Tetrahydro-7-methoxy-4-(methyl-d3)-1 4-benzothiazepine
• Alternative name
  2,3,4,5-Tetrahydro-7-methoxy-4-(methyl-d3)-1,4-benzothiazepine

Gene info

• Identity
  HGNC:37538
• Gene
  PIRC34
• Long gene name
  piwi-interacting RNA cluster 34
• Locus
  7
• Discovery year
  2009-11-05
• Entrez gene record
  100313890
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37537
• Gene
  PIRC33
• Long gene name
  piwi-interacting RNA cluster 33
• Locus
  7
• Discovery year
  2009-11-05
• Entrez gene record
  100313854
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37536
• Gene
  PIRC32
• Long gene name
  piwi-interacting RNA cluster 32
• Locus
  7
• Discovery year
  2009-11-05
• Entrez gene record
  100313811
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:32995
• Gene
  SNORD114-7
• Long gene name
  small nucleolar RNA, C/D box 114-7
• Synonyms
  • 14q(II-7)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767583
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003199.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5633
• Gene
  IGHV3OR15-7
• Long gene name
  immunoglobulin heavy variable 3/OR15-7 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable 3/OR15-7
  • immunoglobulin heavy variable 3/OR15-7 pseudogene
• Synonyms
  • IGHV3/OR15-7
• GenBank acession
  • Z29597
• Locus
  15q11.2
• Discovery year
  2000-04-17
• Entrez gene record
  28318
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000171835

Gene info

• Identity
  HGNC:33026
• Gene
  SNORD115-7
• Long gene name
  small nucleolar RNA, C/D box 115-7
• Synonyms
  • HBII-52-7
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033444
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003299.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:34284
• Gene
  RNU6-7
• Long gene name
  RNA, U6 small nuclear 7
• Synonyms
  • U6-7
• Locus
  14q12
• Discovery year
  2008-06-10
• Entrez gene record
  101954275
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_104084
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:37533
• Gene
  PIRC29
• Long gene name
  piwi-interacting RNA cluster 29
• Locus
  7
• Discovery year
  2009-11-05
• Entrez gene record
  100313927
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37534
• Gene
  PIRC30
• Long gene name
  piwi-interacting RNA cluster 30
• Locus
  7
• Discovery year
  2009-11-05
• Entrez gene record
  100313853
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37535
• Gene
  PIRC31
• Long gene name
  piwi-interacting RNA cluster 31
• Locus
  7
• Discovery year
  2009-11-05
• Entrez gene record
  100313787
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

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