20-Desethyl-20-methyl-10-hydroxy-7-ethylcamptothecin

Chemical available in other sizes

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Stock availability

Pending QC
Cas number

This product doesn't have CAS Number
Chemical s molecular weight

378.38
Chemical s main applications

20-Desethyl-20-methyl-10-hydroxy-7-ethylcamptothecin is an intermediate in the synthesis of Irinotecan Hydrochloride (I767500), a DNA topoisomerase inhibitor and also a derivative of Camptothecin (C175145), an antitumor alkaloid.
Other name

11-Ethyl-4,9-dihydroxy-4-methyl-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Chemical s formula

C21H18N2O5
Physical properties

Brown Solid
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

DMSO
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications
Description

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,

Gene target

20-Desethyl-20-methyl-10-hydroxy-7-ethylcamptothecin
Gene symbol

PIRC104, PIRC103, SNORD115-20, SNORD114-20, SNORD116-20, IGKV3-20, IGLVI-20
Short name

20-Desethyl-20-methyl-10-hydroxy-7-ethylcamptothecin
Alternative name

20-Desethyl-20-methyl-10-hydroxy-7-ethylcamptothecin

Identity

HGNC:5934
Gene

IGLVI-20
Long gene name

immunoglobulin lambda variable (I)-20 (pseudogene)
Synonyms gene name
- immunoglobulin lambda variable (I)-20
- immunoglobulin lambda variable (I)-20 pseudogene
Synonyms
- IGLV(I)-20
GenBank acession
- D87007
Locus

22q11.22
Discovery year

2000-05-08
Entrez gene record

28769
RefSeq identity
- NG_000002
Classification
- Immunoglobulin lambda locus at 22q11.2
VEGA ID

OTTHUMG00000151242