(1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol-d4

• Catalog number
  A603797
• Price
  Please ask
• Size
  1 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Please Inquire
• Cas number
  This product doesn't have CAS Number
• Chemical s molecular weight
  292.37
• Chemical s main applications
  (1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol-d4 is deuterium labeled (1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol (A603795), which is an impurity of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
• Chemical s category
  Impurities, Inhibitors, Isotope Labelled Compounds, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
• Other name
  Abacavir Impurity E
• Chemical s formula
  C14H16D4N6O
• Physical properties
  No Data Available
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  No Data Available
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications

• Gene target
  [2-Amino-6   cyclopropylamino   9H-purin-9-yl]cyclopentanemethanol-d4  
• Gene symbol
  RNU6-9, PIRC45, PIRC47, PIRC38, PIRC43, PIRC37
• Short name
  (1R 3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol-d4
• Alternative name
  (1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol-d4

Gene info

• Identity
  HGNC:34269
• Gene
  RNU6-9
• Long gene name
  RNA, U6 small nuclear 9
• Synonyms
  • U6-9
• Locus
  19p13.3
• Discovery year
  2008-06-10
• Entrez gene record
  101954271
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_104080
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:37549
• Gene
  PIRC45
• Long gene name
  piwi-interacting RNA cluster 45
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313813
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37551
• Gene
  PIRC47
• Long gene name
  piwi-interacting RNA cluster 47
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313859
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37542
• Gene
  PIRC38
• Long gene name
  piwi-interacting RNA cluster 38
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313788
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37547
• Gene
  PIRC43
• Long gene name
  piwi-interacting RNA cluster 43
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313857
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37541
• Gene
  PIRC37
• Long gene name
  piwi-interacting RNA cluster 37
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313812
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

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