(1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol

• Catalog number
  A603795
• Price
  Please ask
• Size
  5 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  In Stock
• Cas number
  208762-35-0
• Chemical s molecular weight
  288.35
• Chemical s main applications
  (1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol is an impurity of Abacavir (A104990). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
• Chemical s category
  Impurities, Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
• Other name
  Abacavir Impurity E
• Chemical s formula
  C14H20N6O
• Physical properties
  Off-White Solid
• Melting temperature
  77-81ºC
• Boiling temperature
  No Data Available
• Chemical s soluble in
  Methanol (Slightly), Water (Slightly)
• Stability conditions
  No Data Available
• Storage
  -20°C Freezer
• Chemical s specifications

• Gene target
  [2-Amino-6   cyclopropylamino   9H-purin-9-yl]cyclopentanemethanol  
• Gene symbol
  RNU6-9, PIRC47, PIRC38, PIRC43, PIRC45, PIRC39, PIRC44
• Short name
  (1R 3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol
• Alternative name
  (1R,3S)-3-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopentanemethanol

Gene info

• Identity
  HGNC:34269
• Gene
  RNU6-9
• Long gene name
  RNA, U6 small nuclear 9
• Synonyms
  • U6-9
• Locus
  19p13.3
• Discovery year
  2008-06-10
• Entrez gene record
  101954271
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_104080
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:37551
• Gene
  PIRC47
• Long gene name
  piwi-interacting RNA cluster 47
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313859
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37542
• Gene
  PIRC38
• Long gene name
  piwi-interacting RNA cluster 38
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313788
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37547
• Gene
  PIRC43
• Long gene name
  piwi-interacting RNA cluster 43
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313857
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37549
• Gene
  PIRC45
• Long gene name
  piwi-interacting RNA cluster 45
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313813
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37543
• Gene
  PIRC39
• Long gene name
  piwi-interacting RNA cluster 39
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313856
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37548
• Gene
  PIRC44
• Long gene name
  piwi-interacting RNA cluster 44
• Locus
  9
• Discovery year
  2009-11-05
• Entrez gene record
  100313908
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

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