10-O-Acetyl SN-38

• Catalog number
  A187735
• Price
  Please ask
• Size
  2 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  In Stock
• Cas number
  946821-59-6
• Chemical s molecular weight
  434.44
• Chemical s main applications
  Protected Irinotecan metabolite.
• Chemical s category
  Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
• Other name
  10-Acetyloxy-7-ethylcamptothecin; 10-Hydroxy-7-ethylcamptothecin 10-Acetate; (4S)-9-(Acetyloxy)-4,11-diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;
• Chemical s formula
  C24H22N2O6
• Physical properties
  Light Beige to Beige Solid
• Melting temperature
  >230ºC (dec.)
• Boiling temperature
  No Data Available
• Chemical s soluble in
  DMSO (Slightly, Heated)
• Stability conditions
  No Data Available
• Storage
  -20°C Freezer, Under inert atmosphere
• Chemical s specifications
• Description
  N terminal acetylation or CH3CO as epigenetic regulation of 10-O- SN-38 by NATs.

• Gene target
  10-O   SN-38  
• Gene symbol
  IGLVI-38, SNORD115-38, IGHV3-38, IGKV2D-38, IGKV2-38, IGHVIII-38-1, CENPO, H4C15, PIRC49
• Short name
  10-O- SN-38
• Alternative name
  10-O-Acetyl SN-38

Gene info

• Identity
  HGNC:5935
• Gene
  IGLVI-38
• Long gene name
  immunoglobulin lambda variable (I)-38 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable (I)-38
  • immunoglobulin lambda variable (I)-38 pseudogene
• Synonyms
  • IGLV(I)-38
• GenBank acession
  • D87009
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28768
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151073

Gene info

• Identity
  HGNC:33057
• Gene
  SNORD115-38
• Long gene name
  small nucleolar RNA, C/D box 115-38
• Synonyms
  • HBII-52-38
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033812
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003353.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5601
• Gene
  IGHV3-38
• Long gene name
  immunoglobulin heavy variable 3-38 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 3-38
• GenBank acession
  • M99669
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28429
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152093

Gene info

• Identity
  HGNC:5803
• Gene
  IGKV2D-38
• Long gene name
  immunoglobulin kappa variable 2D-38 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2D-38
  • immunoglobulin kappa variable 2D-38 pseudogene
• GenBank acession
  • X71892
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28879
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000159961

Gene info

• Identity
  HGNC:5787
• Gene
  IGKV2-38
• Long gene name
  immunoglobulin kappa variable 2-38 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2-38
  • immunoglobulin kappa variable 2-38 pseudogene
• GenBank acession
  • X71888
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28917
• RefSeq identity
  • NG_000834
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151685

Gene info

• Identity
  HGNC:5699
• Gene
  IGHVIII-38-1
• Long gene name
  immunoglobulin heavy variable (III)-38-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (III)-38-1
  • immunoglobulin heavy variable (III)-38-1 pseudogene
• Synonyms
  • IGHV(III)-38-1
• GenBank acession
  • AB019439
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28346
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152090

Gene info

• Identity
  HGNC:28152
• Gene
  CENPO
• Long gene name
  centromere protein O
• Synonyms
  • MGC11266
  • CENP-O
• GenBank acession
  • AK027859
• Locus
  2p23.3
• Discovery year
  2006-06-15
• Entrez gene record
  79172
• Pubmed identfication
  • 16622420
  • 16622419
• RefSeq identity
  • NM_024322
• Classification
  • Constitutive centromere associated network
• VEGA ID
  OTTHUMG00000125525

Gene info

• Identity
  HGNC:29607
• Gene
  H4C15
• Long gene name
  H4 clustered histone 15
• Synonyms gene
  • HIST2H4B
• Synonyms gene name
  • histone 2, H4b
  • histone cluster 2, H4b
  • histone cluster 2 H4 family member b
• Synonyms
  • H4/o
• GenBank acession
  • BC108260
• Locus
  1q21.2
• Discovery year
  2006-06-12
• Entrez gene record
  554313
• Pubmed identfication
  • 15527963
• RefSeq identity
  • NM_001034077
• Classification
  • H4 histones
• VEGA ID
  OTTHUMG00000188201

Gene info

• Identity
  HGNC:37553
• Gene
  PIRC49
• Long gene name
  piwi-interacting RNA cluster 49
• Locus
  10
• Discovery year
  2009-11-05
• Entrez gene record
  100313929
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

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