10-Hydroxy-9-[(dimethylamino)methyl]-5-ethoxy-(20S,5RS)-camptothecin

Chemical available in other sizes

Please inquire size and price
Stock availability

Pending QC
Cas number

504413-76-7
Chemical s molecular weight

465.5
Chemical s main applications

10-Hydroxy-9-[(dimethylamino)methyl]-5-ethoxy-(20S,5RS)-camptothecin is an impurity of Topotecan (T542500), a chemotherapy agent that is a topoisomerase 1 inhibitor.
Chemical s category

Chiral Reagents, Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Other name

(4S)-10-[(Dimethylamino)methyl]-12-ethoxy-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Chemical s formula

C25H27N3O6
Physical properties

Orange Solid
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

DMSO, Methanol
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications
Description

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,

Gene target

10-Hydroxy-9 dimethylamino methyl] 5-ethoxy 20S 5RS camptothecin
Gene symbol

PIRC49, SNORD115-10, SNORD116-10, IGHV3OR16-10, IGKV2OR2-10, ERVK-10
Short name

10-Hydroxy-9-[(dimethylamino)methyl]-5-ethoxy-(20S 5RS)-camptothecin
Alternative name

10-Hydroxy-9-[(dimethylamino)methyl]-5-ethoxy-(20S,5RS)-camptothecin

Identity

HGNC:5806
Gene

IGKV2OR2-10
Long gene name

immunoglobulin kappa variable 2/OR2-10 (pseudogene)
Synonyms gene name
- immunoglobulin kappa variable 2/OR2-10
- immunoglobulin kappa variable 2/OR2-10 pseudogene
Synonyms
- IGKV2/OR2-10
GenBank acession
- X51886
Locus

2q11.2
Discovery year

2000-04-18
Entrez gene record

28855
RefSeq identity
- NG_011661
Classification
- Immunoglobulin kappa (IGK) orphons