1-β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C
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Catalog numberA764007
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PricePlease ask
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Size2,5 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityPlease Inquire
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Cas number1256490-38-6
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Chemical s molecular weight262.24
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Chemical s main applications1-β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C is the labeled analogue of 1-β-D-Arabinofuranosyluracil-2-C-methyl (A764005), an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
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Chemical s categoryCarbohydrates & Derivatives, Heterocycles, Impurities, Isotope Labelled Compounds, Nucleotides, Bases & Related Reagents
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Other name1-(2-C-Methyl-d3, 13C-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyl-d3, 13C-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; Sofosbuvir Impurity 12-d3, 13C
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Chemical s formulaC913CH11D3N2O6
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Physical propertiesNo Data Available
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Melting temperatureNo Data Available
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Boiling temperatureNo Data Available
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Chemical s soluble inNo Data Available
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Stability conditionsNo Data Available
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StorageNo Data Available
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DescriptionA methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
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Gene target
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Gene symbolERVFC1-1, SMC4, PLPP2, BIRC2, PCK1, MYB, MAP3K8, GZMH, PPM1H, SFTPC
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Short name1-β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C
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Alternative name1-β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C
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Gene info
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Identity
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Gene
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Long gene nameendogenous retrovirus group FC1 member 1, envelope
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Synonyms gene name
- endogenous retrovirus group FC1, member 1
- endogenous retrovirus group FC1 member 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2011-05-05
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Entrez gene record
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Pubmed identfication
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Classification
- Envelope ERV derived genes
Gene info
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Identity
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Gene
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Long gene namestructural maintenance of chromosomes 4
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Synonyms gene
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Synonyms gene name
- SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
- SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-02-22
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Entrez gene record
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Pubmed identfication
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Classification
- Structural maintenance of chromosomes proteins
- Condensin I subunits
- Condensin II subunits
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephospholipid phosphatase 2
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Synonyms gene
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Synonyms gene name
- phosphatidic acid phosphatase type 2C
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-02
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Entrez gene record
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Pubmed identfication
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Classification
- Phospholipid phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namebaculoviral IAP repeat containing 2
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Synonyms gene
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Synonyms gene name
- baculoviral IAP repeat-containing 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-06-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Baculoviral IAP repeat containing
- Ring finger proteins
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namephosphoenolpyruvate carboxykinase 1
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Synonyms gene name
- phosphoenolpyruvate carboxykinase 1 (soluble)
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Synonyms
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Locus
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Discovery year1990-09-10
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMYB proto-oncogene, transcription factor
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Synonyms gene name
- v-myb avian myeloblastosis viral oncogene homolog
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Synonyms
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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Classification
- Myb/SANT domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemitogen-activated protein kinase kinase kinase 8
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-09-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mitogen-activated protein kinase kinase kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namegranzyme H
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Synonyms gene
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Synonyms gene name
- granzyme H (cathepsin G-like 2, protein h-CCPX)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1990-04-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Granule associated serine proteases of immune defence
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein phosphatase, Mg2+/Mn2+ dependent 1H
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Synonyms gene
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Synonyms gene name
- ras homolog gene family, member C like 1
- protein phosphatase 1H (PP2C domain containing)
- protein phosphatase, Mg2+/Mn2+ dependent, 1H
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-04-29
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Entrez gene record
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RefSeq identity
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Classification
- Protein phosphatases, Mg2+/Mn2+ dependent
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesurfactant protein C
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Synonyms gene
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Synonyms gene name
- surfactant, pulmonary-associated protein C
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Synonyms
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Synonyms name
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Locus
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Discovery year1988-05-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BRICHOS domain containing
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VEGA ID
