NFkB p65 Antibody (pSer468): APC
-
Catalog numberSPC-1406D-APC
-
PricePlease ask
-
Size100 µl
-
-
TargetNFkB p65 (pSer468)
-
ConjugateAPC
-
Research Area sCancer, Apoptosis, Neuroscience, Neurodegeneration, Alzheimer's Disease, Cell Signaling, Epigenetics and Nuclear Signaling, Nuclear Signaling Pathways, NFkB Pathway, Cardiovascular System, Atherosclerosis, Vascular Inflammation, Inflammatory Mediators, Cell Signaling, Metabolism
-
Alternative Name sp65 Antibody, RELA Antibody, NFkB p65 Antibody, NF- kappaB p65 Antibody, p65 NF kappaB Antibody, OTTHUMP00000233476 Antibody, OTTHUMP00000233473 Antibody, OTTHUMP00000233475 Antibody, V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65 Antibody, p65 NFkB Antibody, RELA Antibody, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 Antibody, Avian reticuloendotheliosis viral (v rel) oncogene homolog A Antibody, v rel reticuloendotheliosis viral oncogene homolog A (avian) Antibody, Nuclear factor of kappa light polypeptide gene enhancer in B cells 3 Antibody, Transcription factor p65 Antibody, OTTHUMP00000233474 Antibody, NF kappa B p65delta3 Antibody, NFKB3 Antibody, TF65_HUMAN Antibody, OTTHUMP00000233900 Antibody, v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)) Antibody, Nuclear Factor NF Kappa B p65 Subunit Antibody, V rel avian reticuloendotheliosis viral oncogene homolog A Antibody, Nuclear factor NF-kappa-B p65 subunit Antibody, MGC131774 Antibody
-
CategoryAntibodies
-
Product TypePolyclonal
-
ImmunogenSynthetic phospho-peptide from human NFkB p65 around the phosphorylation site of serine 468 (pSer468).
-
Immunogen SpeciesHuman
-
Accession NumberNP_001138610.1
-
Gene ID5970
-
Swiss ProtQ04206
-
ApplicationsWB, IHC, IP
-
Host SpeciesRabbit
-
Species ReactivityHuman, Mouse, Rat
-
Antibody DilutionWB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions); optimal dilutions for assays should be determined by the user.
-
PurificationPeptide Affinity Purified
-
Storage BufferPBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
-
SpecificityDetects endogenous levels of NFkB p65 only when phosphorylated at serine 468 (pSer468). Detects a band at ~75 kDa.
-
Storage Temperature-20ºC
-
Shipping TemperatureBlue Ice or 4ºC
-
Cellular LocalizationNucleus, Cytoplasm, Cytosol, Nuclear Chromatin, Nucleoplasm, Transcription Factor Complex, I-Kappab/Nf-Kappab Complex, Nf-Kappab P50/P65 Complex
-
Field of UseFor in vitro research use only.
-
Gross Weight kg1.4
-
Net Weight g0.1
-
PropertiesIf you buy Antibodies supplied by StressMarq they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
GeneNF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
-
French translationanticorps
-
Gene target
-
Gene symbolAPC
-
Short nameNFkB p65 Antibody (pSer468): APC
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeIgG
-
LabelAPC
-
Alternative nameNFkB p65 (antibody to-) (pSer468): adenomatous polyposis coli
-
Alternative techniqueantibodies
-
Alternative to gene targetadenomatous polyposis coli, BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46, APC and IDBG-37007 and ENSG00000134982 and 324, microtubule plus-end binding, nuclei, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233
-
Gene info
-
Identity
-
Gene
-
Long gene nameAPC regulator of WNT signaling pathway
-
Synonyms gene name
- adenomatosis polyposis coli
- adenomatous polyposis coli
- APC, WNT signaling pathway regulator
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Protein phosphatase 1 regulatory subunits
- Armadillo repeat containing
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data