LFM A13,BTK kinase inhibitor

Research Area s

Cell Signaling , Cancer , Apoptosis , Cancer Growth Inhibitors , Tyrosine Kinase Inhibitors
Category

Small Molecules
Product Type

Inhibitor
CAS No

62004-35-7
MolecularFormula

C11H8Br2N2O2
Molecular Weight

360
Purity

≥97% (TLC)
Solubility

Soluble in DMSO (10 mg/ml) or ethanol (0.3 mg/ml)
Appearance

Yellow solid
Storage Temperature

-20°C
Shipping Temperature

Shipped Ambient
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Gene target

LFM A13 BTK kinase inhibitor
Gene symbol

SNAR-A13, BTK
Short name

LFM A13 BTK kinase inhibitor
Alternative name

LFM A13,Bruton agammaglobulinemia tyrosine kinase phosphorylation catalyst suppressor
Alternative to gene target

Bruton agammaglobulinemia tyrosine kinase, AGMX1 and AT and ATK and BPK and IMD1 and PSCTK1 and XLA, BTK and IDBG-79651 and ENSG00000010671 and 695, phosphatidylinositol-3, nuclei, Btk and IDBG-171427 and ENSMUSG00000031264 and 12229, BTK and IDBG-633447 and ENSBTAG00000019250 and 533459

Identity

HGNC:34316
Gene

SNAR-A13
Long gene name

small NF90 (ILF3) associated RNA A13
Synonyms gene name
- small nuclear ILF3/NF90-associated RNA A13
- small ILF3/NF90-associated RNA A13
Synonyms
- snaR-A53139991
GenBank acession
- EU071063
Locus

19q13.33
Discovery year

2008-06-20
Entrez gene record

100169959
Pubmed identfication
- 17855395
RefSeq identity
- NR_024216
Classification
- Small NF90 (ILF3) associated RNAs

Identity

HGNC:1133
Gene

BTK
Long gene name

Bruton tyrosine kinase
Synonyms gene
- AGMX1
- IMD1
Synonyms gene name
- Bruton agammaglobulinemia tyrosine kinase
Synonyms
- ATK
- XLA
- PSCTK1
Synonyms name
- Bruton's tyrosine kinase
GenBank acession
- AK057105
Locus

Xq22.1
Discovery year

1986-01-01
Entrez gene record

695
Pubmed identfication
- 8380905
RefSeq identity
- NM_000061
Classification
- Tec family tyrosine kinases
- SH2 domain containing
- Pleckstrin homology domain containing
VEGA ID

OTTHUMG00000022022
Locus Specific Databases