Active Human Recombinant Tau (K18), P301L mutant Protein Monomer

• Catalog number
  SPR-328B
• Price
  Please ask
• Size
  100 µg

• Target
  Tau
• Research Area s
  Alzheimer's Disease, Axon Markers, Cell Markers, Cell Signaling, Cytoskeleton, Microtubules, MT Associated Proteins, Neurodegeneration, Neuron Markers, Neuroscience, Tangles & Tau
• Alternative Name s
  Active tau monomer, active tau protein monomer, active tau protein, microtubule-associated protein tau, MAPT, MAP, microtubule-associated protein, tau-441, Paired Helical Filament-Tau, Phf-Tau, Neurofibrillary Tangle Protein, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1, Isoform 4, tubulin-associated unit
• Category
  Protein
• Nature
  Recombinant
• Gene ID
   4137
• Swiss Prot
  P10636
• Applications
  WB, SDS-PAGE, In vivo assay, In vitro assay
• Biological Activity
  Thioflavin T emission curve shows increased fluorescence (correlated to tau protein fibrillation) when active tau PFFs are combined with active tau monomers.
• Biological Activity Abreviation
  Active
• Expression System
  E. coli
• Protein Length
  Partial
• Purification
  Ion-exchange Purified
• Storage Buffer
  10 mM HEPES, 100 mM NaCl pH 7.4
• Specificity
  ~15.1 kDa
• Storage Temperature
  -80ºC
• Shipping Temperature
  Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
• Cellular Localization
  Cytoplasm, Axolemma, Axolemma Plasma Membrane, Axon, Cell Body, Cell membrane, Cytoplasmic Ribonucleoprotein Granule, Cytoplasmic Side, Cytoskeleton, Cytosol, Dendrite, Growth cone, Microtubule, Microtubule Associated Complex, Neurofibrillary Tangle, Neuronal Cell Body, Nuclear Periphery, Nuclear Speck, Nucleus, Peripheral membrane protein, Plasma Membrane, Tubulin Complex
• Field of Use
  For in vitro research use only.
• SDS
• Image URLs
  more | details
• Gross Weight kg
  1.4
• Net Weight g
  0.1
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Active   Tau   K18   P301L   mutant   Protein   Monomer  
• Gene symbol
  ERVK-18
• Short name
  Active Recombinant Tau (K18), P301L mutant Protein Monomer
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. StressMarq advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  functionnal H. sapiens Rec. Taurine (K18), P301L mutant Protein Monomer
• Alternative technique
  rec

Gene info

• Identity
  HGNC:39025
• Gene
  ERVK-18
• Long gene name
  endogenous retrovirus group K member 18
• Synonyms gene name
  • endogenous retrovirus group K, member 18
• Synonyms
  • c1_C
  • HERV-K18
• Synonyms name
  • HERV-K_1q23.3 provirus ancestral Env polyprotein
  • endogenous retrovirus K-18
  • IDDMK1,2-22
  • HERV-K_1q23.3 provirus ancestral Pol protein
  • HERV-K_1q23.3 provirus ancestral Pro protein
• GenBank acession
  • FN806828
  • AF012336
• Locus
  1q23.3
• Discovery year
  2011-05-05
• Pubmed identfication
  • 18664271
  • 10516026
  • 21542922

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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