Rabbit Anti-Human YSK4 Polyclonal: ATTO 680
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Catalog numberSPC-1216D-A680
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PricePlease ask
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Size100 µl
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ImmunogenSynthetic peptide corresponding to the N-terminus of human YSK4 (AA1-15)
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Antibody s targetHuman YSK4
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Antibody s full descriptionRabbit Anti-Human YSK4 Polyclonal
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Antibody s categoryPolyclonal Antibodies
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Antibody s other nameEC 2.7.11 Antibody, RCK Antibody, regulated in COPD kinase Antibody, SPS1/STE20-related protein kinase YSK4 Antibody, Yeast Sps1/Ste20-related kinase 4 (S. cerevisiae) Antibody, yeast Sps1/Ste20-related kinase 4 Antibody, YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae) Antibody
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Verified applicationsWB, AM
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Raised inRabbit
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Antibody s reactivityHuman, Mouse
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Antibody s recommended dilutions for useWB (1:250); optimal dilutions for assays should be determined by the user.
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Antibody s purified fromPeptide Affinity Purified
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Recommended buffer for storagePBS pH7.4, 50% glycerol, 0.025% Thimerosal
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Antibody s concentrationSee included datasheet or contact our support service
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Antibody s specificityDetects 150.54 kDa.
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Storage recommendations-20°C
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Shipping recommendationsBlue Ice or 4°C
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Certificate of analysisA 1:250 dilution of SPC-1216 was sufficient for detection of YSK4 in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
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Antibody in cellCytoplasm
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Tissue specificitySee included datasheet or contact our support service.
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Scientific contextYSK4 (YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)), also known as RCK (regulated in COPD, protein kinase), is a 1,328 amino acid protein that belongs to the STE Ser/Thr protein kinase family, STE20 subfamily and protein kinase superfamily. Containing one protein kinase domain, YSK4 exists as six alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 2 and mouse chromosome 1. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome, is due to mutations in the ALMS1 gene.
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BibliographyRefer to PubMed
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Released date29/Aug/2016
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NCBI numberNP_079328
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Gene number80122
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Protein numberQ56UN5
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PubMed numberRefer to PubMed
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Tested applicationsTo be tested
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Tested reactivityTo be tested
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Antibody s datasheetContact our support service to receive datasheet or other technical documentation.
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Representative figure linkNo Data Available
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Warning informationNon-hazardous
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Country of productionCanada
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Total weight kg1.4
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Net weight g0.1
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Stock availabilitIn Stock
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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TestStressMark antibodies supplies antibodies that are for research of human proteins.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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Gene target
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Gene symbolMAP3K19
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Short nameRabbit Anti- YSK4 Polyclonal: ATTO 680
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Techniqueanti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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HostRabbit, Rabbits
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IsotypeImmunoglobulin
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LabelATTO 680
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SpeciesHuman, Humans
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Alternative nameproduction species: rabbit Antibody toHuman YSK4 polyclonal: ATTO 680
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Alternative techniquepolyclonals, rabbit-anti, antibodies
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Gene info
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Identity
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Gene
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Long gene namemitogen-activated protein kinase kinase kinase 19
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Synonyms gene
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Synonyms gene name
- Yeast Sps1/Ste20-related kinase 4 (S. cerevisiae)
- yeast Sps1/Ste20-related kinase 4 (S. cerevisiae)
- YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-05-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mitogen-activated protein kinase kinase kinases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data