Rabbit Anti-Human GUK1 (pTyr53) Polyclonal: PE/ATTO 594
-
Catalog numberSPC-992D-P594
-
PricePlease ask
-
Size100 µl
-
-
ImmunogenA phospho-specific peptide corresponding to residues surrounding Tyr53 of human GUK1 (AA50-56)
-
Antibody s targetHuman GUK1 (pTyr53)
-
Antibody s full descriptionRabbit Anti-Human GUK1 (pTyr53) Polyclonal
-
Antibody s categoryPolyclonal Antibodies
-
Antibody s other nameGMK Antibody, GMP kinase Antibody, Guanylate kinase Antibody, GUK1 Antibody, KGUA_HUMAN Antibody
-
Verified applicationsWB, AM
-
Raised inRabbit
-
Antibody s reactivityHuman
-
Antibody s recommended dilutions for useWB (1:250); optimal dilutions for assays should be determined by the user.
-
Antibody s purified fromPeptide Affinity Purified
-
Recommended buffer for storagePBS pH7.4, 50% glycerol, 0.025% Thimerosal
-
Antibody s concentrationSee included datasheet or contact our support service
-
Antibody s specificityDetects 21.726 kDa.
-
Storage recommendations-20°C
-
Shipping recommendationsBlue Ice or 4°C
-
Certificate of analysisA 1:250 dilution of SPC-992 was sufficient for detection of GUK1 (pTyr53) in 10 µg of human kidney lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
-
Antibody in cellCytosol
-
Tissue specificitySee included datasheet or contact our support service.
-
Scientific contextGUK1 (guanylate kinase 1), also known as GMK (GMP kinase), is a 197 amino acid protein that contains one guanylate kinase-like domain and belongs to the guanylate kinase family. Ubiquitously expressed, GUK1 exists as a monomer that catalyzes the ATP-dependent conversion of GMP to GDP, thereby playing an essential role in the recycling of GMP. Via its catalytic activity, GUK1 is thought to participate in regulating the supply of guanine nucleotides to signal transduction pathways. Overexpression of GUK1 is associated with pituitary adenocarcinomas, suggesting that GUK1 is involved in tumorigenesis.
-
BibliographyRefer to PubMed
-
Released date29/Aug/2016
-
NCBI numberNP_000849
-
Gene number2987
-
Protein numberQ16774
-
PubMed numberRefer to PubMed
-
Tested applicationsTo be tested
-
Tested reactivityTo be tested
-
Antibody s datasheetContact our support service to receive datasheet or other technical documentation.
-
Representative figure linkNo Data Available
-
Warning informationNon-hazardous
-
Country of productionCanada
-
Total weight kg1.4
-
Net weight g0.1
-
Stock availabilitIn Stock
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
TestStressMark antibodies supplies antibodies that are for research of human proteins.
-
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
Gene target
-
Gene symbolGUK1
-
Short nameRabbit Anti- GUK1 (pTyr53) Polyclonal: PE/ATTO 594
-
Techniqueanti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
HostRabbit, Rabbits
-
IsotypeImmunoglobulin
-
LabelPE/ATTO 594
-
SpeciesHuman, Humans
-
Alternative nameproduction species: rabbit Antibody toHuman GUK1 (pTyr53) polyclonal: peroxidase/ATTO 594
-
Alternative techniquepolyclonals, rabbit-anti, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameguanylate kinase 1
-
GenBank acession
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data