Mouse Anti-Human KCNQ2 Monoclonal IgG1, Clone S26A-23

• Catalog number
  SMC-308D-A655
• Price
  Please ask
• Size
  100 µg

• Clone
  S26A-23
• Immunogen
  Fusion protein amino acids 1-59 of human KCNQ2
• Antibody s full description
  Mouse Anti-Human KCNQ2 Monoclonal IgG1 Antibody, Clone: S26A-23: ATTO 655
• Antibody s category
  Monoclonal Antibodies
• Antibody s other name
  BFNC Antibody, EBN1 Antibody, ENB1 Antibody, HNSPC Antibody, KCNA11 Antibody, KQT like 2 Antibody, KV7.2 Antibody, KVEBN1. KvLQT2 Antibody, voltage gated potassium channel subunit Kv7.2 Antibody
• Raised in
  Mouse
• Antibody s target
  KCNQ2
• Primary research fields
  Neuroscience, Ion Channels, Potassium Channels, Voltage-Gated Potassium Channels, Cancer
• Brandname
  None
• Antibodies applications
  WB, IHC, ICC/IF, IP, AM
• Antibody s reactivity
  Human, Mouse, Rat, Hamster
• Antibody s dilutions
  WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
• Purity
  Protein G Purified
• Antibody buffer for storage
  PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Antibody s concentration
  1 mg/ml
• Antibody s specificity
  Detects ~95kDa.
• Storage recommendations
  -20ºC
• Shipping recommendations
  Blue Ice or 4ºC
• Antibody certificate of analysis
  1 µg/ml of SMC-308 was sufficient for detection of KCNQ2 in 10 µg of COS-1 cell lysate transiently expressing KCNQ2 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Antibody in cell
  Membrane
• Tissue specificity
  See included datasheet or contact our support service
• Scientific context
  Kv7.2 (KvLQT2) is a potassium channel protein coded for by the gene KCNQ2. It is associated with benign familial neonatal convulsions (1).
• Bibliography
  1. Wuttke T.V., et al. (2008) J Physiol. 586(2): 545-555.
• Released date
  30-Jul-2009
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• NCBI number
  NP_004509.2
• Gene number
  3785
• Protein number
  O43526
• Antibody s datasheet
  Contact our support service
• Representative figure link
  more | details | see here
• Representative figure legend
  Immunohistochemistry analysis using Mouse Anti-KCNQ2 Monoclonal Antibody, Clone S26A-23 (SMC-308). Tissue: frozen brain section. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-KCNQ2 Monoclonal Antibody (SMC-308) at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Western Blot analysis of Human, hamster HEK and CHO cell lysates showing detection of KCNQ2 protein using Mouse Anti-KCNQ2 Monoclonal Antibody, Clone S26A-23 (SMC-308). Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-KCNQ2 Monoclonal Antibody (SMC-308) at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. KCNQ2 overexpressed. Immunohistochemistry analysis using Mouse Anti-KCNQ2 Monoclonal Antibody, Clone S26A-23 (SMC-308). Tissue: hippocampus. Species: Human. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-KCNQ2 Monoclonal Antibody (SMC-308) at 1:1000 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Mouse Anti-KCNQ2 antibody [S26A-23] used in Immunohistochemistry (IHC) on Mouse frozen brain section (SMC-308) Mouse Anti-KCNQ2 Antibody [S26A-23] used in Western Blot (WB) on Human, hamster HEK and CHO cell lysates (SMC-308) Mouse Anti-KCNQ2 Antibody [S26A-23] used in Immunohistochemistry (IHC) on Human hippocampus (SMC-308)
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  1.4
• Net weight g
  0.1
• Stock availability
  In Stock
• Other related products
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Test
  StressMark antibodies supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Latin name
  Mus musculus

• Gene target
  KCNQ2   Monoclonal   IgG1   S26A-23  
• Gene symbol
  KCNQ2-AS1, IGHV3-23, IGKV2D-23, SNORD116-23, SNORD115-23, SNORD114-23, IGKV2-23, ERVW-23, IGLV2-23, CEMP1
• Short name
  Mouse Anti- KCNQ2 Monoclonal IgG1, Clone S26A-23
• Technique
  anti-Human, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, Monoclonals or monoclonal antibodies, mouses
• Host
  mouse
• Isotype
  IgG1, IgG1
• Label
  ATTO 655
• Species
  Human, Humans, Mouses
• Alternative name
  Mouse Antibody toHuman KCNQ2 monoclonal IgG1, clonality S26A-23
• Alternative technique
  murine, antibodies
• Clone name
  S26A-23

Gene info

• Identity
  HGNC:40321
• Gene
  KCNQ2-AS1
• Long gene name
  KCNQ2 antisense RNA 1
• Locus
  20q13.33
• Discovery year
  2019-08-15
• Entrez gene record
  105372720
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:5588
• Gene
  IGHV3-23
• Long gene name
  immunoglobulin heavy variable 3-23
• GenBank acession
  • M99660
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28442
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152091

Gene info

• Identity
  HGNC:5796
• Gene
  IGKV2D-23
• Long gene name
  immunoglobulin kappa variable 2D-23 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2D-23
  • immunoglobulin kappa variable 2D-23 pseudogene
• GenBank acession
  • X71887
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28886
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151605

Gene info

• Identity
  HGNC:33089
• Gene
  SNORD116-23
• Long gene name
  small nucleolar RNA, C/D box 116-23
• Synonyms
  • HBII-85-23
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033434
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003337
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33042
• Gene
  SNORD115-23
• Long gene name
  small nucleolar RNA, C/D box 115-23
• Synonyms
  • HBII-52-23
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033800
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003315.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33011
• Gene
  SNORD114-23
• Long gene name
  small nucleolar RNA, C/D box 114-23
• Synonyms
  • 14q(II-23)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767603
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003216.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5780
• Gene
  IGKV2-23
• Long gene name
  immunoglobulin kappa variable 2-23 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2-23
  • immunoglobulin kappa variable 2-23 pseudogene
• GenBank acession
  • X71885
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28924
• RefSeq identity
  • NG_000834
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151638

Gene info

• Identity
  HGNC:49311
• Gene
  ERVW-23
• Long gene name
  endogenous retrovirus group W member 23
• Synonyms gene name
  • endogenous retrovirus group W, member 23
• GenBank acession
  • HG421062
• Locus
  12p13.31
• Discovery year
  2013-10-21

Gene info

• Identity
  HGNC:5890
• Gene
  IGLV2-23
• Long gene name
  immunoglobulin lambda variable 2-23
• GenBank acession
  • X14616
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28813
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151234

Gene info

• Identity
  HGNC:32553
• Gene
  CEMP1
• Long gene name
  cementum protein 1
• Synonyms
  • CP-23
• Synonyms name
  • cementum protein-23
• GenBank acession
  • AY584596
• Locus
  16p13.3
• Discovery year
  2006-09-19
• Entrez gene record
  752014
• Pubmed identfication
  • 16263347
• RefSeq identity
  • NM_001048212
• VEGA ID
  OTTHUMG00000177160

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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