WISP-1 Recombinant Protein

• Catalog number
  40-217
• Price
  Please ask
• Size
  0.005 mg, 0.02 mg

• About recombinant protein
  WISP-1 is a member of the CCN family of secreted cysteine rich regulatory proteins. It is expressed in the heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. WISP-1 is a beta catenin regulated protein that can contribute to tumorigenesis and has also been shown to play a role in bone development and fracture repair. Human WISP-1 is a 38.1 kDa protein containing 346 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cystine knot-like (CTCK) domain.
• Other name of the recombinant
  CCN4, WISP1c, WISP1i, WISP1tc, CCN4, WNT1-inducible-signaling pathway protein 1, CCN family member 4, WISP-1
• Recombinant in
  E. coli
• SEQUENCE
  TALSPAPTTM DFTPAPLEDT SSRPQFCKWP CECPPSPPRC PLGVSLITDG CECCKMCAQQ LGDNCTEAAI CDPHRGLYCD YSGDRPRYAI GVCAQVVGVG CVLDGVRYNN GQSFQPNCKY NCTCIDGAVG CTPLCLRVRP PRLWCPHPRR VSIPGHCCEQ WVCEDDAKRP RKTAPRDTGA FDAVGEVEAW HRNCIAYTSP WSPCSTSCGL GVSTRISNVN AQCWPEQESR LCNLRPCDVD IHTLIKAGKK CLAVYQPEAS MNFTLAGCIS TRSYQPKYCG VCMDNRCCIP YKSKTIDVSF QCPDGLGFSR QVLWINACFC NLSCRNPNDI FADLESYPDF SEIAN
• Activity
  The ED50 was determined by the dose - dependant proliferation of the MCF - 7 cell line. The expected ED50 for this effect is 1.0 - 3.0 μg/mL.
• Keep at
  The lyophilized WISP-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted WISP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing WISP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  325910845
• Accession nr
  NP_001191799.1
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  8840
• Gene name
  WNT1 inducible signaling pathway protein 1
• Source
  Homo sapiens
• Uniprot
  O95388
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  WISP-1   Protein  
• Gene symbol
  WISP1
• Short name
  WISP-1 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  WISP-1 Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:12769
• Gene
  CCN4
• Long gene name
  cellular communication network factor 4
• Synonyms gene
  • WISP1-OT1
  • WISP1-UT1
  • WISP1
• Synonyms gene name
  • WISP1 overlapping transcript 1
  • WISP1 3'UTR-associated RNA 1
  • WISP1 overlapping transcript 1 (non-protein coding)
  • WNT1 inducible signaling pathway protein 1
• Synonyms
  • WISP-1
• GenBank acession
  • AF100779
• Locus
  8q24.22
• Discovery year
  1999-01-22
• Entrez gene record
  8840
• Pubmed identfication
  • 9843955
• RefSeq identity
  • NM_003882
• Classification
  • Cellular communication network factors
• VEGA ID
  OTTHUMG00000164440

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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